Trevi Therapeutics, Inc.

Report azionario NasdaqGM:TRVI

Capitalizzazione di mercato: US$2.0b

Trevi Therapeutics Gestione

Criteri Gestione verificati 3/4

Trevi Therapeutics Il CEO è Jennifer Good, nominato in Mar2011, e ha un mandato di 15.17 anni. la retribuzione annua totale è $ 3.94M, composta da 15.8% di stipendio e 84.2% di bonus, comprese azioni e opzioni aziendali. possiede direttamente 0.15% delle azioni della società, per un valore di $ 3.02M. La durata media del mandato del team dirigenziale e del consiglio di amministrazione è rispettivamente 5.1 anni e 9 anni.

Informazioni chiave

Jennifer Good

Amministratore delegato

US$3.9m

Compenso totale

Percentuale dello stipendio del CEO15.78%
Mandato del CEO15.2yrs
Proprietà del CEO0.2%
Durata media del management5.1yrs
Durata media del Consiglio di amministrazione9yrs

Aggiornamenti recenti sulla gestione

Recent updates

Seeking Alpha Apr 17

Trevi Therapeutics: Late-Stage Transition Meets Execution Risk

Summary Trevi Therapeutics is transitioning to a late-stage biotech, prioritizing Haduvio for IPF-related chronic cough as its lead indication. TRVI's strong cash position, bolstered by a $150M stock offering, funds operations into 2028 and reduces near-term financing risk. Haduvio's Phase 3 trials in IPF chronic cough, with quantifiable endpoints and safety focus, are the pivotal near-term catalysts for TRVI. Despite a premium valuation (P/B 10.2x–16.3x), TRVI's upside relies on successful late-stage execution; I recommend holding until Phase 3 data. Read the full article on Seeking Alpha
Nuova narrazione Mar 19

Chronic Cough Trials And Focused Pulmonologist Reach Will Support Long Term Upside Potential

Catalysts About Trevi Therapeutics Trevi Therapeutics is a clinical stage biopharmaceutical company developing Haduvio for chronic cough conditions associated with fibrotic lung diseases and refractory chronic cough. What are the underlying business or industry changes driving this perspective?
Nuova narrazione Mar 05

Chronic Cough Platform And Strong Cash Runway Will Support Future Upside Potential

Catalysts About Trevi Therapeutics Trevi Therapeutics is a clinical stage biopharmaceutical company developing Haduvio, an extended release formulation of nalbuphine, for multiple chronic cough indications where there are currently no FDA approved therapies. What are the underlying business or industry changes driving this perspective?
Articolo di analisi Apr 02

We Think Trevi Therapeutics (NASDAQ:TRVI) Can Afford To Drive Business Growth

Even when a business is losing money, it's possible for shareholders to make money if they buy a good business at the...
Articolo di analisi Sep 27

We Think Trevi Therapeutics (NASDAQ:TRVI) Can Afford To Drive Business Growth

There's no doubt that money can be made by owning shares of unprofitable businesses. For example, although...
Articolo di analisi May 24

We Think Trevi Therapeutics (NASDAQ:TRVI) Can Afford To Drive Business Growth

We can readily understand why investors are attracted to unprofitable companies. For example, biotech and mining...
Articolo di analisi Jan 27

Trevi Therapeutics (NASDAQ:TRVI) Is In A Good Position To Deliver On Growth Plans

We can readily understand why investors are attracted to unprofitable companies. For example, although...
Seeking Alpha Sep 19

Trevi adds 19% on full data set from mid-stage cough study

Clinical-stage biopharma, Trevi Therapeutics, Inc. (NASDAQ:TRVI) gained 19% pre-market Monday after the company announced complete data from its Phase 2 trial for lead asset Haduvio for the treatment of chronic cough in idiopathic pulmonary fibrosis (IPF) U.K.-based CANAL study was designed to compare Haduvio, an oral extended-release formulation of pain therapy nalbuphine, against placebo in terms of the mean daytime cough frequency at Day 22 as the primary endpoint, as measured by an objective cough monitor. The full set of subjects (N=38) reached the primary endpoint with statistical significance indicating a 52.5% change in daytime cough frequency for Haduvio compared to placebo (p<0.0001). The reduction of cough frequency stood at ~76.1% and 25.3% in Haduvio and placebo arms, respectively. The safety profile was in line with data from previous studies for the treatment, and two adverse events were found to be unrelated to the experimental therapy. TRVI expects to start the next trial for this indication in H1 2023. A previous readout from 26 patients in the CANAL trial indicated a 52% placebo-adjusted reduction in daytime cough events for Haduvio.
Seeking Alpha Sep 11

Trevi Therapeutics: Moving Forward

Summary Today, we put Busted IPO Trevi Therapeutics in the spotlight for the first time ever. The company's primary drug candidate Haduvio is moving towards late-stage development as a treatment for prurigo nodularis as well as chronic cough in adults with idiopathic pulmonary fibrosis. An investment analysis follows in the paragraphs below. "It's not unpatriotic to denounce an injustice committed on our behalf, perhaps it's the most patriotic thing we can do."― E.A. Bucchianeri Today, we take our first look at Trevi Therapeutics Inc. (TRVI). The small biopharma firm came public just over three years ago and is deep in Busted IPO territory even with a nice rebound in the shares so far in 2022. What lies ahead for Trevi Therapeutics? An analysis follows below. Seeking Alpha Company Overview Trevi Therapeutics is a clinical-stage biopharmaceutical company based out of New Haven, CT. The company focuses on the development of medicines to treat serious neurologically mediated conditions. Its primary asset in development is Haduvio which is an oral extended-release formulation of nalbuphine. Nalbuphine is a mixed ĸ-opioid receptor agonist and µ-opioid receptor antagonist that has been approved and marketed as an injectable for pain indications for more than 20 years in the United States and Europe. Haduvio has a dual mechanism of action by acting as both an antagonist (blocker) to the body's mu opioid receptor and as an agonist (activator) to the kappa opioid receptor. March Company Presentation This candidate is currently being evaluating for the treatment of prurigo nodularis or PN and chronic cough in adults with idiopathic pulmonary fibrosis or IPF. Chronic cough represents a significant unmet need for IPF patients, as the majority of these patients report this cough as one of their most bothersome aspects of their disease. March Company Presentation Haduvio or Nalbuphine Extended Release [ER] has also been granted Fast Track designation by the FDA for the treatment of itch in patients with prurigo nodularis. In 2011, Endo Pharmaceuticals partnered with Trevi to develop and market compounds incorporating nalbuphine hydrochloride. The stock currently trades just over three bucks a share and sports an approximate market capitalization of $140 million. Pipeline Developments Company Website The stock got a bump in late June 29th when the company disclosed that Haduvio had met key goals in a Phase 2b/3 'PRISM' study for patients with prurigo nodularis. 25% met the primary efficacy endpoint, a clinical measure called 4-point reduction in the Worst Itch - Numerical Rating Scale compared to just 14% of the placebo group. March Company Presentation Patients are currently completing the one-year open-label extension study, which should be over in January. The company is in the process of having an end of Phase 2 meeting with the FDA to discuss the data, next steps and the design for a registrational study that could lead to approval dependent on results. The company would like to do a six-month study with three treatment groups. March Company Presentation Four months before, interim data from a Phase 2 trial evaluating Haduvio to treat IPF suffering from chronic cough found a 52% placebo-adjusted reduction in daytime cough events and the compound was well tolerated. Full results should be out by the end of this quarter. A meeting with the FDA should happen to soon to move this effort to the next stage of development. The company believes this will begin in the first half of 2023. Haduvio could have other potential indications in this category (see above) for other indications. March Company Presentation Analyst Commentary & Balance Sheet Aegis Capital, Oppenheimer and Needham have all reiterated Buy ratings on TRVI over the past four months. All have identical $10 price targets on the stock.
Articolo di analisi Mar 23

Is Trevi Therapeutics (NASDAQ:TRVI) Using Too Much Debt?

Howard Marks put it nicely when he said that, rather than worrying about share price volatility, 'The possibility of...

Analisi delle retribuzioni degli amministratori delegati

Come è cambiata la remunerazione di Jennifer Good rispetto agli utili di Trevi Therapeutics?
DataCompenso totaleStipendioUtili della società
Mar 31 2026n/an/a

-US$46m

Dec 31 2025US$4mUS$622k

-US$43m

Sep 30 2025n/an/a

-US$46m

Jun 30 2025n/an/a

-US$47m

Mar 31 2025n/an/a

-US$47m

Dec 31 2024US$3mUS$608k

-US$48m

Sep 30 2024n/an/a

-US$44m

Jun 30 2024n/an/a

-US$39m

Mar 31 2024n/an/a

-US$34m

Dec 31 2023US$2mUS$597k

-US$29m

Sep 30 2023n/an/a

-US$27m

Jun 30 2023n/an/a

-US$27m

Mar 31 2023n/an/a

-US$28m

Dec 31 2022US$898kUS$523k

-US$29m

Sep 30 2022n/an/a

-US$32m

Jun 30 2022n/an/a

-US$31m

Mar 31 2022n/an/a

-US$33m

Dec 31 2021US$2mUS$506k

-US$34m

Sep 30 2021n/an/a

-US$35m

Jun 30 2021n/an/a

-US$35m

Mar 31 2021n/an/a

-US$33m

Dec 31 2020US$1mUS$478k

-US$33m

Sep 30 2020n/an/a

-US$30m

Jun 30 2020n/an/a

-US$30m

Mar 31 2020n/an/a

-US$29m

Dec 31 2019US$3mUS$435k

-US$27m

Compensazione vs Mercato: La retribuzione totale di Jennifer ($USD 3.94M ) è circa la media per le aziende di dimensioni simili nel mercato US ($USD 5.45M ).

Compensazione vs guadagni: La retribuzione di Jennifer è aumentata nonostante l'azienda non sia redditizia.


AMMINISTRATORE DELEGATO

Jennifer Good (60 yo)

15.2yrs
Mandato
US$3,944,892
Compensazione

Ms. Jennifer L. Good co-founded Trevi Therapeutics, Inc., in March 2011 and has been its Chief Executive Officer and President since March 2011 and had been its Interim Principal Financial Officer since Au...


Gruppo dirigente

NomePosizioneMandatoCompensazioneProprietà
Jennifer Good
Co-Founder15.2yrsUS$3.94m0.15%
$ 3.0m
James Cassella
Chief Development Officer1.7yrsUS$1.64m0%
$ 0
Farrell Simon
Chief Commercial Officer5.7yrsUS$1.36m0.057%
$ 1.2m
Thomas Sciascia
Co-Founder & Chief Scientific Officer15.2yrsUS$977.13k0.16%
$ 3.1m
David Hastings
Chief Financial Officer & Principal Financial Officerless than a yearNessun datoNessun dato
Christopher Galletta
Controller & Chief Accounting Officer5.1yrsNessun dato0.018%
$ 369.5k
Katie McManus
Communications Managerno dataNessun datoNessun dato
Katherine Takaki
Senior VP of Global Regulatory Affairs1.3yrsNessun datoNessun dato
5.1yrs
Durata media
64yo
Età media

Gestione esperta: Il team dirigenziale di TRVI è esperto e expertise (durata media dell'incarico 5.1 anni).


Membri del Consiglio di amministrazione

NomePosizioneMandatoCompensazioneProprietà
Jennifer Good
Co-Founder15.2yrsUS$3.94m0.15%
$ 3.0m
Anne VanLent
Independent Director7.6yrsUS$283.43k0.018%
$ 367.9k
Dominick Colangelo
Independent Director5.9yrsUS$275.93k0%
$ 0
Edward Mathers
Independent Director8.8yrsUS$265.93k0%
$ 0
David Meeker
Independent Chairman of the Board8.8yrsUS$293.43k0.25%
$ 5.0m
Michael Heffernan
Independent Director9.3yrsUS$283.43k0.0045%
$ 89.9k
Jeffrey Bernhard
Member of Clinical Advisory Board13.2yrsNessun datoNessun dato
Dawn McGuire
Member of Clinical Advisory Board13.2yrsNessun datoNessun dato
9.0yrs
Durata media
63yo
Età media

Consiglio di amministrazione esperto: I membri del consiglio di amministrazione di TRVI sono considerati esperti (durata media dell'incarico 9 anni).


Analisi aziendale e situazione dei dati finanziari

DatiUltimo aggiornamento (ora UTC)
Analisi dell'azienda2026/05/22 08:06
Prezzo dell'azione a fine giornata2026/05/22 00:00
Utili2026/03/31
Utili annuali2025/12/31

Fonti dei dati

I dati utilizzati nella nostra analisi aziendale provengono da S&P Global Market Intelligence LLC. I seguenti dati sono utilizzati nel nostro modello di analisi per generare questo report. I dati sono normalizzati, il che può comportare un ritardo nella disponibilità della fonte.

PacchettoDatiTempisticaEsempio Fonte USA *
Dati finanziari della società10 anni
  • Conto economico
  • Rendiconto finanziario
  • Bilancio
Stime di consenso degli analisti+3 anni
  • Previsioni finanziarie
  • Obiettivi di prezzo degli analisti
Prezzi di mercato30 anni
  • Prezzi delle azioni
  • Dividendi, scissioni e azioni
Proprietà10 anni
  • Top azionisti
  • Insider trading
Gestione10 anni
  • Team di leadership
  • Consiglio di amministrazione
Sviluppi principali10 anni
  • Annunci aziendali

* Esempio per i titoli statunitensi, per i titoli non statunitensi si utilizzano forme e fonti normative equivalenti.

Se non specificato, tutti i dati finanziari si basano su un periodo annuale ma vengono aggiornati trimestralmente. Si tratta dei cosiddetti dati TTM (Trailing Twelve Month) o LTM (Last Twelve Month). Per saperne di più.

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Fonti analitiche

Trevi Therapeutics, Inc. è coperta da 16 analisti. 9 di questi analisti ha fornito le stime di fatturato o di utile utilizzate come input per il nostro report. Le stime degli analisti vengono aggiornate nel corso della giornata.

AnalistaIstituzione
null nullBMO Capital Markets Equity Research
Mayank MamtaniB. Riley Securities, Inc.
William WoodB. Riley Securities, Inc.