Protagonist Therapeutics, Inc.

NasdaqGM:PTGX Stock Report

Market Cap: US$5.3b

Protagonist Therapeutics Past Earnings Performance

Past criteria checks 2/6

Protagonist Therapeutics has been growing earnings at an average annual rate of 44.8%, while the Biotechs industry saw earnings growing at 22.8% annually. Revenues have been growing at an average rate of 54.6% per year. Protagonist Therapeutics's return on equity is 7.1%, and it has net margins of 21.9%.

Key information

44.83%

Earnings growth rate

46.09%

EPS growth rate

Biotechs Industry Growth17.04%
Revenue growth rate54.61%
Return on equity7.11%
Net Margin21.94%
Last Earnings Update30 Sep 2025

Recent past performance updates

Recent updates

Why Johnson & Johnson Is Eyeing Protagonist Therapeutics: The Rationale

Oct 13

Protagonist Therapeutics, Inc.'s (NASDAQ:PTGX) 51% Price Boost Is Out Of Tune With Revenues

Oct 11
Protagonist Therapeutics, Inc.'s (NASDAQ:PTGX) 51% Price Boost Is Out Of Tune With Revenues

Subdued Growth No Barrier To Protagonist Therapeutics, Inc. (NASDAQ:PTGX) With Shares Advancing 27%

Jun 13
Subdued Growth No Barrier To Protagonist Therapeutics, Inc. (NASDAQ:PTGX) With Shares Advancing 27%

Protagonist Therapeutics: Much More Than Rusfertide In Place To Carry It

Mar 11

Protagonist Therapeutics, Inc.'s (NASDAQ:PTGX) Shares Climb 44% But Its Business Is Yet to Catch Up

Mar 11
Protagonist Therapeutics, Inc.'s (NASDAQ:PTGX) Shares Climb 44% But Its Business Is Yet to Catch Up

Protagonist: Rusfertide PV Data Q1 2025 Isn't The Only 2025 Catalyst On Deck

Jan 13

The Prognosis For Protagonist Therapeutics: Solid Prospects, But Stock Is Pricey

Oct 16

Protagonist Therapeutics: Why I Remain On Sidelines Despite Obvious Promise

Feb 25

Protagonist: Too Many Red Flags

Jun 08

Protagonist Is Still Being Undervalued Like There's Real Risk

Feb 01

Revenue & Expenses Breakdown

How Protagonist Therapeutics makes and spends money. Based on latest reported earnings, on an LTM basis.


Earnings and Revenue History

NasdaqGM:PTGX Revenue, expenses and earnings (USD Millions)
DateRevenueEarningsG+A ExpensesR&D Expenses
30 Sep 252094642148
30 Jun 252095241144
31 Mar 252085640140
31 Dec 2443427543138
30 Sep 2432417143132
30 Jun 2431917040127
31 Mar 2431516240126
31 Dec 2360-7933120
30 Sep 230-14032121
30 Jun 230-13831116
31 Mar 231-14030117
31 Dec 2227-12732126
30 Sep 2235-13032135
30 Jun 2245-13333146
31 Mar 2247-12232138
31 Dec 2127-12627126
30 Sep 2124-10825107
30 Jun 2127-812386
31 Mar 2131-702080
31 Dec 2029-661975
30 Sep 2026-651871
30 Jun 2017-731776
31 Mar 202-831771
31 Dec 190-771665
30 Sep 190-741563
30 Jun 192-661554
31 Mar 1922-451457
31 Dec 1831-391459
30 Sep 1840-281357
30 Jun 1843-241256
31 Mar 1831-311250
31 Dec 1720-371246
30 Sep 179-451143
30 Jun 170-481038
31 Mar 170-40931
31 Dec 160-38726
30 Sep 160-32521
30 Jun 160-28419
31 Mar 160-24415
31 Dec 150-15312

Quality Earnings: PTGX has high quality earnings.

Growing Profit Margin: PTGX's current net profit margins (21.9%) are lower than last year (52.8%).


Free Cash Flow vs Earnings Analysis


Past Earnings Growth Analysis

Earnings Trend: PTGX has become profitable over the past 5 years, growing earnings by 44.8% per year.

Accelerating Growth: PTGX's has had negative earnings growth over the past year, so it can't be compared to its 5-year average.

Earnings vs Industry: PTGX had negative earnings growth (-73.1%) over the past year, making it difficult to compare to the Biotechs industry average (52.4%).


Return on Equity

High ROE: PTGX's Return on Equity (7.1%) is considered low.


Return on Assets


Return on Capital Employed


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Company Analysis and Financial Data Status

DataLast Updated (UTC time)
Company Analysis2025/11/17 11:34
End of Day Share Price 2025/11/14 00:00
Earnings2025/09/30
Annual Earnings2024/12/31

Data Sources

The data used in our company analysis is from S&P Global Market Intelligence LLC. The following data is used in our analysis model to generate this report. Data is normalised which can introduce a delay from the source being available.

PackageDataTimeframeExample US Source *
Company Financials10 years
  • Income statement
  • Cash flow statement
  • Balance sheet
Analyst Consensus Estimates+3 years
  • Forecast financials
  • Analyst price targets
Market Prices30 years
  • Stock prices
  • Dividends, Splits and Actions
Ownership10 years
  • Top shareholders
  • Insider trading
Management10 years
  • Leadership team
  • Board of directors
Key Developments10 years
  • Company announcements

* Example for US securities, for non-US equivalent regulatory forms and sources are used.

Unless specified all financial data is based on a yearly period but updated quarterly. This is known as Trailing Twelve Month (TTM) or Last Twelve Month (LTM) Data. Learn more.

Analysis Model and Snowflake

Details of the analysis model used to generate this report is available on our Github page, we also have guides on how to use our reports and tutorials on Youtube.

Learn about the world class team who designed and built the Simply Wall St analysis model.

Industry and Sector Metrics

Our industry and section metrics are calculated every 6 hours by Simply Wall St, details of our process are available on Github.

Analyst Sources

Protagonist Therapeutics, Inc. is covered by 24 analysts. 12 of those analysts submitted the estimates of revenue or earnings used as inputs to our report. Analysts submissions are updated throughout the day.

AnalystInstitution
Etzer DaroutBarclays
Etzer DaroutBMO Capital Markets Equity Research
Evan SeigermanBMO Capital Markets Equity Research