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Durability Data And Real-World Evidence Will Shape Risk And Opportunity Ahead

Published
06 Aug 24
Updated
27 Nov 25
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AnalystConsensusTarget's Fair Value
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1Y
20.5%
7D
-0.6%

Author's Valuation

US$93.948.3% undervalued intrinsic discount

AnalystConsensusTarget Fair Value

Last Update 27 Nov 25

EW: Durable Outcomes And Low-Risk Data Will Guide Forward Opportunity And Uncertainty

Edwards Lifesciences' average analyst price target has moved higher. Increases range from $4 to $10, as analysts cite a strong Q3, upbeat guidance, and growing confidence in key clinical results as drivers for their upward revisions.

Analyst Commentary

Recent Street research has highlighted a mix of optimism and caution regarding Edwards Lifesciences, as analysts weigh strong quarterly performance and favorable clinical momentum against certain lingering risks and valuation considerations.

Bullish Takeaways

  • Bullish analysts point to strong Q3 results with outperformance in key segments. They highlight particularly robust growth in transcatheter aortic valve replacement (TAVR).
  • Confidence in the durability and adoption of TAVR is reinforced by positive seven-year clinical data, which could drive greater implantation rates in low-risk patients.
  • Upward revisions to future guidance, including increases in top-line and adjusted EPS outlook, are viewed as indicators of sustained operational momentum.
  • Potential catalysts such as changes in National Coverage Determination may further expand the market opportunity and accelerate growth.

Bearish Takeaways

  • Bearish analysts remain sensitive to recent share price pressure driven by investor concerns surrounding key low-risk TAVR data and its implications for future referral patterns.
  • Some caution is expressed regarding the sustainability of margin improvements and whether recent upside is already reflected in current valuations.
  • Analysts note that while current clinical data helps reassure the market and practitioners, any negative surprises in upcoming datasets could impact sentiment and estimates.
  • Uncertainty around long-term competitive dynamics and ongoing investor skepticism about broader sector trends continue to temper enthusiasm.

What's in the News

  • The company recently completed a significant share repurchase, buying back 7.77% of its shares for a total of $3.46 billion. This was part of a program announced in July 2022. (Key Developments)
  • Edwards Lifesciences raised its full-year 2025 sales growth guidance to the high end of 9% to 10%. (Key Developments)
  • New product data highlights successful patient outcomes for mitral and tricuspid therapies. Pivotal trial results for the SAPIEN M3 and EVOQUE systems showed strong performance in safety, effectiveness, and quality-of-life improvements. (Key Developments)
  • Seven-year PARTNER 3 trial data reaffirm the long-term benefits and durability of the SAPIEN 3 transcatheter aortic valve. The results show comparable performance to surgical alternatives and sustained positive health outcomes. (Key Developments)
  • The company announced the planned mid-2026 transition of Chief Financial Officer Scott Ullem. A search has been initiated for his successor while ensuring continuity through his advisory role. (Key Developments)

Valuation Changes

  • Fair Value remains unchanged at $93.94, reflecting consistent analyst assessment of intrinsic worth.
  • Discount Rate has increased slightly from 7.73% to 7.73%, a minor shift likely reflecting updated risk considerations.
  • Revenue Growth projection has risen modestly from 9.88% to 9.91%. This indicates a slight improvement in long-term sales expectations.
  • Net Profit Margin estimate is essentially stable, moving fractionally lower from 24.03% to 24.01%.
  • Future P/E ratio has edged higher from 34.57x to 34.95x. This suggests moderately increased expectations for future earnings relative to share price.

Key Takeaways

  • Strategic product launches, like the TAVR approval and EVOQUE, position Edwards for significant revenue growth and expanded market share.
  • Investments in surgical innovation and operational efficiency mitigate financial threats, enhance global therapy adoption, and stabilize earnings.
  • Tariffs, competitive pressures, and strategic investments could impact Edwards Lifesciences' margins and revenue growth, requiring careful financial planning to achieve targets.

Catalysts

About Edwards Lifesciences
    Provides products and technologies to treat advanced cardiovascular diseases in the United States, Europe, Japan, and internationally.
What are the underlying business or industry changes driving this perspective?
  • The expected approval of the early TAVR indication in the second quarter, along with policy and guideline changes in the U.S. and globally, represents a multiyear growth opportunity that could significantly enhance revenue streams in the future.
  • The planned launch of the transcatheter tricuspid valve EVOQUE in 2024 is anticipated to uniquely position Edwards to gain market share and increase revenues as it becomes the first company to develop and offer this therapy.
  • The recent approval of the Sapien M3 in Europe as the world's first transcatheter mitral valve replacement system signals Edwards' ability to address large, unmet patient needs, which could result in substantial revenue growth.
  • Edwards' ongoing investments in surgical innovation, such as the RESILIA tissue technology, are likely to expand access and adoption of its cardiovascular therapies globally, potentially improving net margins and bolstering revenue.
  • The company's plan to mitigate the financial impacts of announced tariffs and the JenaValve acquisition while maintaining its EPS guidance of $2.40 to $2.50 demonstrates an operational efficiency that could positively impact earnings.

Edwards Lifesciences Earnings and Revenue Growth

Edwards Lifesciences Future Earnings and Revenue Growth

Assumptions

How have these above catalysts been quantified?
  • Analysts are assuming Edwards Lifesciences's revenue will grow by 10.0% annually over the next 3 years.
  • Analysts assume that profit margins will shrink from 24.8% today to 23.7% in 3 years time.
  • Analysts expect earnings to reach $1.8 billion (and earnings per share of $3.09) by about September 2028, up from $1.4 billion today. However, there is some disagreement amongst the analysts with the more bearish ones expecting earnings as low as $1.5 billion.
  • In order for the above numbers to justify the analysts price target, the company would need to trade at a PE ratio of 35.1x on those 2028 earnings, up from 33.2x today. This future PE is greater than the current PE for the US Medical Equipment industry at 29.7x.
  • Analysts expect the number of shares outstanding to decline by 0.46% per year for the next 3 years.
  • To value all of this in today's terms, we will use a discount rate of 7.42%, as per the Simply Wall St company report.

Edwards Lifesciences Future Earnings Per Share Growth

Edwards Lifesciences Future Earnings Per Share Growth

Risks

What could happen that would invalidate this narrative?
  • Edwards Lifesciences faces potential financial risks due to the impact of tariffs, which could affect the company's gross margins and net earnings, as they anticipate a $0.05 EPS impact from current tariffs in 2025, with greater impacts expected in 2026.
  • The acquisition of JenaValve may lead to an EPS dilution of $0.05 to $0.10, which could strain operating margins and necessitate careful planning to offset the acquisition costs in order to maintain earnings per share targets.
  • The competitive pressure in international markets, such as Japan, is exerting downward pressure on TAVR procedure growth, potentially impacting revenue growth and expansion efforts in these regions.
  • While Edwards anticipates expanding TAVR indications to asymptomatic patients, the regulatory and policy changes required for this may take longer than expected, delaying the projected revenues from this expanded patient base.
  • High levels of discretionary R&D spending, as well as necessary strategic investments to offset EPS impacts, indicate that operating expenses could rise, potentially impacting net profit margins if the expected growth in revenues does not materialize accordingly.

Valuation

How have all the factors above been brought together to estimate a fair value?
  • The analysts have a consensus price target of $87.731 for Edwards Lifesciences based on their expectations of its future earnings growth, profit margins and other risk factors. However, there is a degree of disagreement amongst analysts, with the most bullish reporting a price target of $101.0, and the most bearish reporting a price target of just $72.0.
  • In order for you to agree with the analyst's consensus, you'd need to believe that by 2028, revenues will be $7.6 billion, earnings will come to $1.8 billion, and it would be trading on a PE ratio of 35.1x, assuming you use a discount rate of 7.4%.
  • Given the current share price of $79.8, the analyst price target of $87.73 is 9.0% higher. The relatively low difference between the current share price and the analyst consensus price target indicates that they believe on average, the company is fairly priced.
  • We always encourage you to reach your own conclusions though. So sense check these analyst numbers against your own assumptions and expectations based on your understanding of the business and what you believe is probable.

How well do narratives help inform your perspective?

Disclaimer

AnalystConsensusTarget is a tool utilizing a Large Language Model (LLM) that ingests data on consensus price targets, forecasted revenue and earnings figures, as well as the transcripts of earnings calls to produce qualitative analysis. The narratives produced by AnalystConsensusTarget are general in nature and are based solely on analyst data and publicly-available material published by the respective companies. These scenarios are not indicative of the company's future performance and are exploratory in nature. Simply Wall St has no position in the company(s) mentioned. Simply Wall St may provide the securities issuer or related entities with website advertising services for a fee, on an arm's length basis. These relationships have no impact on the way we conduct our business, the content we host, or how our content is served to users. The price targets and estimates used are consensus data, and do not constitute a recommendation to buy or sell any stock, and they do not take account of your objectives, or your financial situation. Note that AnalystConsensusTarget's analysis may not factor in the latest price-sensitive company announcements or qualitative material.

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