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U.S. Pharmaceuticals & Biotech Stocks - Biggest Losers Today

UPDATED Apr 27, 2026

Explore the U.S. (NYSE and NASDAQ) Biggest Losers Today. These Pharmaceuticals & Biotech Stocks have seen the largest drop in Market Cap from the previous trading day.

712 companies
CompanyLast Price1D Return1Y ReturnMarket CapAnalysts TargetValuationGrowthDiv Yield
LLY
US$868.27-1.8%-1.0%US$791.0bUS$1,202.3437.618.0%0.8%
JNJ
US$225.34-0.9%45.1%US$547.6bUS$252.4225.88.3%2.4%
MRK
US$110.23-1.5%32.5%US$276.4bUS$129.7414.98.7%3.1%
GILD
US$127.73-2.0%20.1%US$161.9bUS$158.3618.68.6%2.6%
AMGN
US$340.15-1.3%20.2%US$185.9bUS$352.7323.88.4%3.0%
ABBV
US$197.38-0.7%2.6%US$351.5bUS$249.2783.423.6%3.5%
BMY
US$57.78-1.6%19.2%US$119.9bUS$63.0416.7-0.6%4.4%
PFE
US$26.79-0.8%16.2%US$153.6bUS$28.9319.7-3.0%6.4%
VRTX
US$426.01-1.0%-14.2%US$109.4bUS$548.3927.414.2%n/a
WAT
US$299.79-3.3%-11.8%US$30.4bUS$385.5045.818.8%n/a
BNTX
US$102.06-3.2%-1.9%US$26.7bUS$130.807.76.0%n/a
MRNA
US$48.69-4.0%77.3%US$20.1bUS$46.109.948.3%n/a
RVMD
US$131.67-2.7%217.5%US$28.5bUS$174.3017.054.1%n/a
ERAS
US$19.15-10.9%1,267.9%US$6.7bUS$20.0018.3-7.4%n/a
REGN
US$744.51-0.9%21.9%US$76.5bUS$878.0216.811.7%0.5%
TMO
US$468.04-0.4%11.1%US$174.6bUS$620.5425.411.0%0.4%
CMPX
US$1.78-64.6%-6.3%US$905.8mUS$12.171.660.7%n/a
BIIB
US$180.67-2.0%51.7%US$27.1bUS$212.3620.510.0%n/a
CYTK
US$61.60-5.7%49.4%US$8.1bUS$92.9486.948.3%n/a
PRAX
US$330.99-4.0%809.1%US$9.6bUS$634.2410.563.6%n/a
ELAN
US$22.09-2.9%132.3%US$11.4bUS$28.792.372.2%n/a
WST
US$302.20-1.3%39.8%US$21.6bUS$349.8539.310.2%0.3%
ONC
US$298.90-0.6%19.8%US$33.4bUS$408.20115.533.4%n/a
TGTX
US$35.38-3.4%-15.8%US$5.4bUS$44.5711.711.2%n/a
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