Japanese (NIKKEI) Pharmaceuticals & Biotech Stocks - Biggest Losers Today

UPDATED Dec 24, 2025

Explore the Japanese (NIKKEI) Biggest Losers Today. These Pharmaceuticals & Biotech Stocks have seen the largest drop in Market Cap from the previous trading day.

88 companies
CompanyLast Price1D Return1Y ReturnMarket CapAnalysts TargetValuationGrowthDiv Yield
4519
Chugai Pharmaceutical
JP¥8,266.00-0.9%18.5%JP¥13.6tJP¥8,621.43PE34.3xE11.5%1.2%
4578
Otsuka Holdings
JP¥9,102.00-0.9%6.0%JP¥4.8tJP¥9,731.82PE10.7xE-4.4%1.5%
4503
Astellas Pharma
JP¥2,093.00-0.6%37.6%JP¥3.7tJP¥1,884.62PE30xE1.4%3.7%
4528
Ono Pharmaceutical
JP¥2,175.00-1.4%37.0%JP¥1.0tJP¥1,709.09PE21.1xE-0.5%3.7%
4507
Shionogi
JP¥2,776.00-0.4%26.4%JP¥2.4tJP¥2,572.22PE13.8xE0.7%2.4%
4536
Santen Pharmaceutical
JP¥1,628.50-1.2%4.0%JP¥523.7bJP¥2,141.25PE16.7xE11.4%2.3%
4587
PeptiDream
JP¥1,611.50-2.0%-37.6%JP¥208.2bJP¥3,033.33PS11.6xE44.9%n/a
4887
Sawai Group Holdings
JP¥2,340.00-1.4%9.4%JP¥270.2bJP¥2,533.33PE874.6xE28.5%2.4%
4516
Nippon Shinyaku
JP¥5,790.00-0.9%45.2%JP¥390.3bJP¥6,200.00PE12.2xE-10.4%2.1%
4553
Towa Pharmaceutical
JP¥3,685.00-1.6%13.4%JP¥181.4bJP¥3,880.00PE8.8xE1.3%2.2%
2395
Shin Nippon Biomedical Laboratories
JP¥1,733.00-3.4%3.3%JP¥72.1bJP¥2,440.00PE15.5xE10.1%2.9%
4592
SanBio
JP¥1,597.00-1.4%118.2%JP¥115.0bJP¥2,070.00PB233.7xE44.7%n/a
4552
JCR Pharmaceuticals
JP¥725.00-1.8%23.1%JP¥88.4bJP¥675.00PS2.3xE35.7%2.8%
4540
Tsumura
JP¥4,121.00-0.5%-11.9%JP¥306.3bJP¥4,508.00PE11.2xE3.0%3.7%
4563
AnGes
JP¥58.00-6.5%13.7%JP¥22.4bn/aPS27.4xn/an/a
4559
Zeria Pharmaceutical
JP¥2,087.00-1.3%-13.3%JP¥92.0bJP¥2,400.00PE16.4xE17.5%2.3%
4554
Fuji Pharma
JP¥1,854.00-2.5%16.4%JP¥45.3bJP¥2,150.00PE15.1xE7.9%2.5%
4593
Healios K.K
JP¥299.00-2.6%82.3%JP¥34.5bJP¥665.00PS355.8xE37.9%n/a
4569
KYORIN Pharmaceutical
JP¥1,533.00-0.9%5.1%JP¥88.1bJP¥1,300.00PE9.4xE-17.7%3.7%
4894
Cuorips
JP¥5,790.00-1.5%27.0%JP¥47.7bn/aPS132.6xn/an/a
4599
StemRIM
JP¥256.00-4.1%-11.1%JP¥15.9bJP¥700.00PB2.3xE16.6%n/a
4577
Daito PharmaceuticalLtd
JP¥1,343.00-1.5%32.8%JP¥39.8bJP¥1,200.00PE20xE17.2%3.0%
4886
ASKA Pharmaceutical HoldingsLtd
JP¥2,049.00-0.7%-0.5%JP¥58.2bJP¥2,500.00PE12.2xE2.9%2.7%
4530
Hisamitsu Pharmaceutical
JP¥4,323.00-0.1%6.3%JP¥302.8bJP¥4,325.00PE15.4xE0.3%2.1%
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