Global Biotech Breakthroughs

Sichuan Kelun-Biotech Biopharmaceutical

Market Cap: HK$106.6b

A biopharmaceutical company, engages in the research and development, manufacturing, and commercialization of novel drugs in oncology, immunology, and other therapeutic areas in the People’s Republic of China and internationally.

Ascentage Pharma Group International

Market Cap: HK$33.7b

A clinical-stage biotechnology company, develops therapies for cancers, chronic hepatitis B virus (HBV), and age-related diseases in Mainland China.

CARsgen Therapeutics Holdings

Market Cap: HK$11.7b

An investment holding company, engages in discovering, developing, and commercializing chimeric antigen receptor T (CAR-T) cell therapies for the treatment of hematological malignancies, solid tumors, and autoimmune diseases in China.

Alnylam Pharmaceuticals

Market Cap: US$59.6b

Alnylam Pharmaceuticals, Inc. discovers, develops, and commercializes therapeutics based on ribonucleic acid interference.

Caris Life Sciences

Market Cap: US$11.1b

An artificial intelligence TechBio company, provides molecular profiling services in the United States and internationally.

Xbrane Biopharma

Market Cap: SEK 438.2m

A biotechnology company, engages in the development, manufacture, and sale of biosimilars.

Akeso

Market Cap: HK$158.8b

A biopharmaceutical company, engages in the research, development, manufacture, and commercialization of antibody drugs worldwide.

Mereo BioPharma Group

Market Cap: US$270.5m

A biopharmaceutical company, develops and commercializes therapeutics for the treatment of oncology and rare diseases in the United Kingdom, the United States, and internationally.

Legend Biotech

Market Cap: US$6.6b

Through its subsidiaries, operates as a biopharmaceutical company that discovers, develops, manufactures, and commercializes novel cell therapies for oncology and other indications in the United States, China, and Europe.

Guard Therapeutics International

Market Cap: SEK 449.7m

A pharmaceutical company, identifies, develops, and commercializes therapies for the diagnosis and treatment of acute kidney injuries in Sweden.

Beijing Luzhu Biotechnology

Market Cap: HK$5.0b

A biotechnology company, focuses on the research and development, production, and sale of human vaccines and therapeutic biologics to prevent and control infectious diseases, and treat cancer and autoimmune diseases in Mainland China.

ARS Pharmaceuticals

Market Cap: US$1.3b

A biopharmaceutical company, develops and commercializes treatments for severe allergic reactions.

Madrigal Pharmaceuticals

Market Cap: US$9.2b

A biopharmaceutical company, focuses on delivering novel therapeutics for metabolic dysfunction-associated steatohepatitis (MASH) in the United States.

Achieve Life Sciences

Market Cap: US$149.2m

A late-stage pharmaceutical company, develops and commercializes cytisinicline for nicotine independence in Canada, the United States, and the United Kingdom.

Aldeyra Therapeutics

Market Cap: US$348.0m

A biotechnology company, discovers and develops therapies designed to treat immune-mediated and metabolic diseases.

Xspray Pharma

Market Cap: SEK 1.6b

A pharmaceutical company, engages in the development of protein kinase inhibitors for targeted cancer treatments in Sweden.

Vanda Pharmaceuticals

Market Cap: US$280.7m

A biopharmaceutical company, focuses on the development and commercialization of therapies to address high unmet medical needs worldwide.

Tenaya Therapeutics

Market Cap: US$184.2m

A clinical-stage biotechnology company, discovers, develops, and delivers therapies for heart disease in the United States.

Soleno Therapeutics

Market Cap: US$3.6b

A clinical-stage biopharmaceutical company, focuses on the development and commercialization of novel therapeutics for the treatment of rare diseases.

OS Therapies

Market Cap: US$79.1m

A clinical stage biopharmaceutical company, focuses on the identification, development, and commercialization of treatments for osteosarcoma and other solid tumors in the United States.

Valneva

Market Cap: €858.0m

A specialty vaccine company, develops, manufactures, and commercializes prophylactic vaccines for infectious diseases with unmet needs.

Capricor Therapeutics

Market Cap: US$324.6m

A clinical-stage biotechnology company, engages in the development of transformative cell and exosome-based therapeutics for treating duchenne muscular dystrophy (DMD) and other diseases with unmet medical needs in the United States.

RenovoRx

Market Cap: US$34.5m

A clinical-stage biopharmaceutical company, engages in the developing of targeted combination therapies to enhance therapeutic outcomes for cancer patients undergoing treatment.

Immutep

Market Cap: AU$374.3m

A late-stage biotechnology company, engages in developing novel LAG-3 related immunotherapies for cancer and autoimmune diseases in Australia.

AC Immune

Market Cap: US$212.7m

A clinical stage biopharmaceutical company, discovers, designs, and develops medicines, and therapeutic and diagnostic products for the prevention and treatment of neurodegenerative diseases associated with protein misfolding.

Lipigon Pharmaceuticals

Market Cap: SEK 26.7m

Develops drugs for lipid related diseases in Sweden.

Oxford Biomedica

Market Cap: UK£651.3m

A contract development and manufacturing organization, focuses on delivering therapies to patients worldwide.

Arcutis Biotherapeutics

Market Cap: US$1.9b

A biopharmaceutical company, focuses on developing and commercializing treatments for dermatological diseases.

Aelis Farma

Market Cap: €17.7m

A clinical-stage biopharmaceutical company, focuses on discovering and developing drug candidates for the treatment of central nervous system disorders in France.

Syndax Pharmaceuticals

Market Cap: US$1.4b

A commercial-stage biopharmaceutical company, develops therapies for the treatment of cancer.

aTyr Pharma

Market Cap: US$524.2m

A clinical stage biotechnology company, engages in the discovery and development of product candidates that translate tRNA synthetase biology into new therapies for fibrosis and inflammation in the United States.

GNI Group

Market Cap: JP¥148.3b

Engages in the research, development, manufacture, and sale of pharmaceutical drugs in Japan and internationally.

Shanghai Rightongene Biotechnology

Market Cap: CN¥1.7b

Shanghai Rightongene Biotechnology Co., Ltd.

Ocugen

Market Cap: US$315.4m

A biopharmaceutical company, focuses on discovering, developing, and commercializing novel gene and cell therapies, biologic, and vaccines that improve patients’ health.

XOMA Royalty

Market Cap: US$413.4m

Operates as a biotech royalty aggregator in the United States and the Asia Pacific.

Kuros Biosciences

Market Cap: CHF 1.0b

Engages in the commercialization and development of biologic technologies for musculoskeletal care in the United States of America, the European Union, and internationally.