Global Biotech Breakthroughs

Alnylam Pharmaceuticals

Market Cap: US$38.1b

Alnylam Pharmaceuticals, Inc. discovers, develops, and commercializes therapeutics based on ribonucleic acid interference.

Elicera Therapeutics

Market Cap: SEK 314.0m

A clinical stage immuno-oncology company, develops cell and gene therapies for immune-based cancer treatments in Sweden.

Akeso

Market Cap: HK$77.2b

A biopharmaceutical company, engages in the research, development, manufacturing, and commercialization of antibody drugs.

Ardelyx

Market Cap: US$954.6m

Ardelyx, Inc. discovers, develops, and commercializes medicines to treat unmet medical needs in the United States and internationally.

Innate Pharma

Market Cap: €181.4m

Operates as a biotechnology company that develops immunotherapies for cancer patients in France and internationally.

Blueprint Medicines

Market Cap: US$6.6b

A precision therapy company, develops medicines for genomically defined cancers and blood disorders in the United States and internationally.

Legend Biotech

Market Cap: US$5.2b

Through its subsidiaries, operates as a biopharmaceutical company that discovers, develops, manufactures, and commercializes novel cell therapies for oncology and other indications in the United States, China, and Europe.

Guard Therapeutics International

Market Cap: SEK 313.6m

A pharmaceutical company, identifies, develops, and commercializes therapies for the diagnosis and treatment of acute kidney injuries in Sweden.

Sichuan Kelun-Biotech Biopharmaceutical

Market Cap: HK$72.8b

A biopharmaceutical company, engages in the research and development, manufacturing, and commercialization of novel drugs in oncology, immunology, and other therapeutic areas in the People’s Republic of China and internationally.

Beijing Luzhu Biotechnology

Market Cap: HK$4.1b

A biotechnology company, focuses on the research and development, production, and sale of human vaccines and therapeutic biologics to prevent and control infectious diseases, and treat cancer and autoimmune diseases in China.

Capricor Therapeutics

Market Cap: US$508.3m

A clinical-stage biotechnology company, engages in the development of transformative cell and exosome-based therapeutics for treating duchenne muscular dystrophy (DMD) and other diseases with unmet medical needs in the United States.

Aldeyra Therapeutics

Market Cap: US$134.8m

A biotechnology company, discovers and develops therapies designed to treat immune-mediated and metabolic diseases.

Madrigal Pharmaceuticals

Market Cap: US$6.2b

A biopharmaceutical company, focuses on delivering novel therapeutics for metabolic dysfunction-associated steatohepatitis (MASH) in the United States.

SpringWorks Therapeutics

Market Cap: US$3.5b

A commercial-stage biopharmaceutical company, engages in the development and commercialization of medicines for underserved patient populations suffering from rare diseases and cancer.

Tenaya Therapeutics

Market Cap: US$71.9m

A clinical-stage biotechnology company, discovers, develops, and delivers therapies for heart disease in the United States.

Abeona Therapeutics

Market Cap: US$313.0m

A clinical-stage biopharmaceutical company, develops gene and cell therapies for life-threatening diseases.

RenovoRx

Market Cap: US$44.6m

A clinical-stage biopharmaceutical company, engages in the developing of targeted combination therapies to enhance therapeutic outcomes for cancer patients undergoing treatment.

Soleno Therapeutics

Market Cap: US$3.7b

A clinical-stage biopharmaceutical company, focuses on the development and commercialization of novel therapeutics for the treatment of rare diseases.

Silence Therapeutics

Market Cap: US$242.8m

A biotechnology company, engages in the discovery and development of novel molecules incorporating short interfering ribonucleic acid (siRNA) to inhibit the expression of specific target genes in hematology, cardiovascular, and rare diseases.

Vanda Pharmaceuticals

Market Cap: US$254.6m

A biopharmaceutical company, focuses on the development and commercialization of therapies to address high unmet medical needs worldwide.

Checkpoint Therapeutics

Market Cap: US$349.7m

A commercial -stage immunotherapy and targeted oncology company, focuses on the acquisition, development, and commercialization of novel treatments for patients with solid tumor cancers in the United States and internationally.

ARS Pharmaceuticals

Market Cap: US$1.4b

A biopharmaceutical company, develops and commercializes treatments for severe allergic reactions.

Vicore Pharma Holding

Market Cap: SEK 1.9b

A clinical-stage pharmaceutical company, develops therapies for the treatment of respiratory diseases in Sweden.

OS Therapies

Market Cap: US$31.4m

A clinical stage biopharmaceutical company, focuses on the identification, development, and commercialization of treatments for osteosarcoma and other solid tumors in the United States.

Immutep

Market Cap: AU$430.8m

A late-stage biotechnology company, engages in developing novel LAG-3 related immunotherapies for cancer and autoimmune diseases in Australia.

Kidswell Bio

Market Cap: JP¥8.2b

Develops pharmaceuticals for the treatment of rare and intractable diseases in Japan.

aTyr Pharma

Market Cap: US$333.8m

A clinical stage biotechnology company, engages in the discovery and development of product candidates that translate tRNA synthetase biology into new therapies for fibrosis and inflammation in the United States.

Oxford Biomedica

Market Cap: UK£321.7m

A contract development and manufacturing organization, focuses on delivering therapies to patients worldwide.

Arcutis Biotherapeutics

Market Cap: US$1.6b

A biopharmaceutical company, focuses on developing and commercializing treatments for dermatological diseases.

CollPlant Biotechnologies

Market Cap: US$23.4m

A regenerative and aesthetic medicine company, focuses on three-dimensional (3D) bioprinting of tissues and organs, and medical aesthetics in the United States, Canada, Israel, Europe, and internationally.

Aelis Farma

Market Cap: €16.7m

A clinical-stage biopharmaceutical company, focuses on discovering and developing drug candidates for the treatment of central nervous system disorders in France.

GNI Group

Market Cap: JP¥124.1b

Engages in the research, development, manufacture, and sale of pharmaceutical drugs in Japan and internationally.

Shanghai Rightongene Biotechnology

Market Cap: CN¥1.3b

Shanghai Rightongene Biotechnology Co., Ltd.

ABL Bio

Market Cap: ₩3.2t

A biotech research company, focuses on the development of therapeutic drugs for immuno-oncology and neurodegenerative diseases.

XOMA Royalty

Market Cap: US$300.6m

Operates as a biotech royalty aggregator in the United States and the Asia Pacific.

TuHURA Biosciences

Market Cap: US$144.6m

A clinical stage immuno-oncology company, that develops novel technologies for the treatment of cancer immunotherapies.