Global Biotech Breakthroughs

Madrigal Pharmaceuticals

Market Cap: US$10.0b

A biopharmaceutical company, focuses on delivering novel therapeutics for metabolic dysfunction-associated steatohepatitis (MASH) in the United States.

Ascelia Pharma

Market Cap: SEK 409.2m

A biotech company, develops identifies, develops, and commercializes novel drugs to treat orphan oncology treatments in Sweden.

Travere Therapeutics

Market Cap: US$2.8b

A biopharmaceutical company, identifies, develops, and delivers therapies to people living with rare kidney and metabolic diseases in the United States.

CARsgen Therapeutics Holdings

Market Cap: HK$8.7b

An investment holding company, engages in discovering, developing, and commercializing chimeric antigen receptor T (CAR-T) cell therapies for the treatment of hematological malignancies, solid tumors, and autoimmune diseases in China.

Sichuan Kelun-Biotech Biopharmaceutical

Market Cap: HK$97.1b

A biopharmaceutical company, engages in the research and development, manufacturing, and commercialization of novel drugs in oncology, immunology, and other therapeutic areas in the People’s Republic of China and internationally.

Arcutis Biotherapeutics

Market Cap: US$3.1b

A biopharmaceutical company, focuses on developing and commercializing treatments for dermatological diseases.

Devyser Diagnostics

Market Cap: SEK 1.6b

Engages in the development, manufacture, and sale of diagnostic kits and solutions for DNA testing within hereditary diseases, oncology, and post-transplantation monitoring in Sweden, rest of Europe, the Middle East, Africa, North and South America, and Asia.

Insmed

Market Cap: US$35.5b

Develops and commercializes therapies for patients with serious and rare diseases in the United States, Europe, Japan, and internationally.

Ardelyx

Market Cap: US$1.4b

Ardelyx, Inc. discovers, develops, and commercializes medicines to treat unmet medical needs in the United States and internationally.

Marker Therapeutics

Market Cap: US$24.2m

A clinical-stage immuno-oncology company, engages in the development and commercialization of novel T cell-based immunotherapies for the treatment of hematological malignancies and solid tumor indications.

Akeso

Market Cap: HK$100.5b

A biopharmaceutical company, engages in the research, development, manufacture, and commercialization of antibody drugs worldwide.

SanBio

Market Cap: JP¥176.2b

Engages in the development, production, and sale of regenerative cell medicines for the central nervous system.

Cogent Biosciences

Market Cap: US$6.0b

A clinical-stage biotechnology company, focuses on developing precision therapies for genetically defined diseases.

Suzhou Zelgen Biopharmaceuticals

Market Cap: CN¥25.0b

Engages in the research, development, manufacture, sale, and distribution of medicines in the People's Republic of China.

Mesoblast

Market Cap: AU$3.1b

Engages in the development of regenerative medicine products in Australia, the United States, Singapore, and Switzerland.

Guard Therapeutics International

Market Cap: SEK 34.3m

A clinical-stage biotechnology company, identifies and develops medicines to treat kidney diseases in Sweden.

Cutia Therapeutics

Market Cap: HK$1.9b

An investment holding company, engages in the research, development, manufacture, and commercialization of scalp diseases and care products, and skin care products in the People’s Republic of China and Hong Kong.

Dizal (Jiangsu) Pharmaceutical

Market Cap: CN¥25.0b

A biopharmaceutical company, discovers, develops, and commercializes therapeutics for the treatment of cancer and immunological diseases.

Pelthos Therapeutics

Market Cap: US$75.2m

A bio-pharmaceutical company, develops and commercializes therapeutic products to help patients with unmet treatment burdens.

Valneva

Market Cap: €825.3m

A specialty vaccine company, develops, manufactures, and commercializes prophylactic vaccines for infectious diseases with unmet needs.

Capricor Therapeutics

Market Cap: US$1.5b

A clinical-stage biotechnology company, engages in the development of transformative cell and exosome-based therapeutics for treating duchenne muscular dystrophy (DMD) and other diseases with unmet medical needs in the United States.

Achieve Life Sciences

Market Cap: US$227.3m

A late-stage pharmaceutical company, develops and commercializes cytisinicline for nicotine independence in Canada, the United States, and the United Kingdom.

Lineage Cell Therapeutics

Market Cap: US$438.6m

A clinical-stage biotechnology company, develops novel cell therapies for neurological and ophthalmic conditions in the United States and internationally.

RenovoRx

Market Cap: US$33.5m

A clinical-stage biopharmaceutical company, engages in the developing of targeted combination therapies to enhance therapeutic outcomes for cancer patients undergoing treatment.

Soleno Therapeutics

Market Cap: US$2.1b

A clinical-stage biopharmaceutical company, focuses on the development and commercialization of novel therapeutics for the treatment of rare diseases.

Initiator Pharma

Market Cap: SEK 234.1m

A clinical stage life science company, develops drugs targeting unmet medical needs within the central and peripheral nervous system.

Aldeyra Therapeutics

Market Cap: US$297.8m

A biotechnology company, discovers and develops therapies designed to treat immune-mediated and metabolic diseases.

ARS Pharmaceuticals

Market Cap: US$889.6m

A biopharmaceutical company, develops and commercializes treatments for severe allergic reactions.

Qyuns Therapeutics

Market Cap: HK$4.5b

A clinical-stage biotech company, engages in the research and development of biologic therapies for autoimmune and allergic diseases in the People’s Republic of China.

Caris Life Sciences

Market Cap: US$5.5b

An artificial intelligence TechBio company, provides molecular profiling services in the United States and internationally.

Precigen

Market Cap: US$1.5b

A discovery and clinical-stage biopharmaceutical company, develops gene and cell therapies using precision technology to target diseases in areas of immuno-oncology, autoimmune disorders, and infectious diseases.

Viridian Therapeutics

Market Cap: US$2.6b

Engages in discovering, developing, and commercializing treatments for serious and rare diseases.

CollPlant Biotechnologies

Market Cap: US$8.9m

A regenerative and aesthetic medicine company, focuses on three-dimensional (3D) bioprinting of tissues and organs, and medical aesthetics in the United States, Canada, Israel, Europe, and internationally.

Syndax Pharmaceuticals

Market Cap: US$1.7b

A commercial-stage biopharmaceutical company, develops therapies for the treatment of cancer.

AC Immune

Market Cap: US$249.3m

A clinical stage biopharmaceutical company, discovers, designs, and develops medicines, and therapeutic and diagnostic products for the prevention and treatment of neurodegenerative diseases associated with protein misfolding.

Medivir

Market Cap: SEK 752.0m

A pharmaceutical company, focuses on the development and commercialization of treatments for cancer in Sweden, the Nordic region, rest of Europe, and internationally.