Global Biotech Breakthroughs

Alnylam Pharmaceuticals

Market Cap: US$43.3b

Alnylam Pharmaceuticals, Inc. discovers, develops, and commercializes therapeutics based on ribonucleic acid interference.

CARsgen Therapeutics Holdings

Market Cap: HK$11.9b

An investment holding company, engages in discovering, developing, and commercializing chimeric antigen receptor T (CAR-T) cell therapies for the treatment of hematological malignancies, solid tumors, and autoimmune diseases in China.

Xbrane Biopharma

Market Cap: SEK 380.3m

A biotechnology company, engages in the development, manufacture, and sale of biosimilars.

Ardelyx

Market Cap: US$1.0b

Ardelyx, Inc. discovers, develops, and commercializes medicines to treat unmet medical needs in the United States and internationally.

Akeso

Market Cap: HK$101.4b

A biopharmaceutical company, engages in the research, development, manufacture, and commercialization of antibody drugs worldwide.

Mereo BioPharma Group

Market Cap: US$456.3m

A biopharmaceutical company, develops and commercializes therapeutics for the treatment of oncology and rare diseases in the United Kingdom, the United States, and internationally.

Innate Pharma

Market Cap: €140.6m

Operates as a biotechnology company that develops immunotherapies for cancer patients in France and internationally.

Guard Therapeutics International

Market Cap: SEK 350.9m

A pharmaceutical company, identifies, develops, and commercializes therapies for the diagnosis and treatment of acute kidney injuries in Sweden.

Legend Biotech

Market Cap: US$6.6b

Through its subsidiaries, operates as a biopharmaceutical company that discovers, develops, manufactures, and commercializes novel cell therapies for oncology and other indications in the United States, China, and Europe.

Blueprint Medicines

Market Cap: US$8.3b

A precision therapy company, develops medicines for genomically defined cancers and blood disorders in the United States and internationally.

Tenaya Therapeutics

Market Cap: US$99.5m

A clinical-stage biotechnology company, discovers, develops, and delivers therapies for heart disease in the United States.

Capricor Therapeutics

Market Cap: US$468.5m

A clinical-stage biotechnology company, engages in the development of transformative cell and exosome-based therapeutics for treating duchenne muscular dystrophy (DMD) and other diseases with unmet medical needs in the United States.

Vanda Pharmaceuticals

Market Cap: US$292.9m

A biopharmaceutical company, focuses on the development and commercialization of therapies to address high unmet medical needs worldwide.

Soleno Therapeutics

Market Cap: US$4.4b

A clinical-stage biopharmaceutical company, focuses on the development and commercialization of novel therapeutics for the treatment of rare diseases.

RenovoRx

Market Cap: US$49.7m

A clinical-stage biopharmaceutical company, engages in the developing of targeted combination therapies to enhance therapeutic outcomes for cancer patients undergoing treatment.

Abeona Therapeutics

Market Cap: US$301.3m

A clinical-stage biopharmaceutical company, develops gene and cell therapies for life-threatening diseases.

Madrigal Pharmaceuticals

Market Cap: US$6.6b

A biopharmaceutical company, focuses on delivering novel therapeutics for metabolic dysfunction-associated steatohepatitis (MASH) in the United States.

Aldeyra Therapeutics

Market Cap: US$257.6m

A biotechnology company, discovers and develops therapies designed to treat immune-mediated and metabolic diseases.

ARS Pharmaceuticals

Market Cap: US$1.6b

A biopharmaceutical company, develops and commercializes treatments for severe allergic reactions.

Achieve Life Sciences

Market Cap: US$112.2m

A late-stage pharmaceutical company, develops and commercializes cytisinicline for nicotine independence in Canada, the United States, and the United Kingdom.

OS Therapies

Market Cap: US$54.3m

A clinical stage biopharmaceutical company, focuses on the identification, development, and commercialization of treatments for osteosarcoma and other solid tumors in the United States.

Sichuan Kelun-Biotech Biopharmaceutical

Market Cap: HK$80.5b

A biopharmaceutical company, engages in the research and development, manufacturing, and commercialization of novel drugs in oncology, immunology, and other therapeutic areas in the People’s Republic of China and internationally.

Beijing Luzhu Biotechnology

Market Cap: HK$4.4b

A biotechnology company, focuses on the research and development, production, and sale of human vaccines and therapeutic biologics to prevent and control infectious diseases, and treat cancer and autoimmune diseases in China.

Oxford Biomedica

Market Cap: UK£355.0m

A contract development and manufacturing organization, focuses on delivering therapies to patients worldwide.

Lipigon Pharmaceuticals

Market Cap: SEK 19.0m

Develops drugs for lipid related diseases in Sweden.

Aelis Farma

Market Cap: €13.2m

A clinical-stage biopharmaceutical company, focuses on discovering and developing drug candidates for the treatment of central nervous system disorders in France.

Precigen

Market Cap: US$478.2m

A discovery and clinical-stage biopharmaceutical company, develops gene and cell therapies using precision technology to target diseases in areas of immuno-oncology, autoimmune disorders, and infectious diseases.

Arcutis Biotherapeutics

Market Cap: US$1.6b

A biopharmaceutical company, focuses on developing and commercializing treatments for dermatological diseases.

aTyr Pharma

Market Cap: US$472.6m

A clinical stage biotechnology company, engages in the discovery and development of product candidates that translate tRNA synthetase biology into new therapies for fibrosis and inflammation in the United States.

Kidswell Bio

Market Cap: JP¥10.0b

Develops pharmaceuticals for the treatment of rare and intractable diseases in Japan.

Immutep

Market Cap: AU$365.1m

A late-stage biotechnology company, engages in developing novel LAG-3 related immunotherapies for cancer and autoimmune diseases in Australia.

Devyser Diagnostics

Market Cap: SEK 2.2b

Engages in the development, manufacture, and sale of diagnostic kits and solutions for DNA testing within hereditary diseases, oncology, and post-transplantation monitoring in Sweden, rest of Europe, the Middle East, Africa, North and South America, and Asia.

XOMA Royalty

Market Cap: US$322.6m

Operates as a biotech royalty aggregator in the United States and the Asia Pacific.

Invivyd

Market Cap: US$88.2m

A biopharmaceutical company, focuses on the discovery, development, and commercialization of antibody-based solutions for infectious diseases in the United States.

TuHURA Biosciences

Market Cap: US$115.4m

A clinical stage immuno-oncology company, that develops novel technologies for the treatment of cancer immunotherapies.

ABL Bio

Market Cap: ₩3.0t

A biotech research company, focuses on the development of therapeutic drugs for immuno-oncology and neurodegenerative diseases.