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AMPH: Q3 Drug Trends And Buybacks Will Shape Balanced Near-Term Outlook

Update shared on 13 Dec 2025

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4.9%

Analysts have modestly lowered their price target on Amphastar Pharmaceuticals to $31 from $32, citing recent Q3 pricing and volume trends for key drugs and a largely unchanged outlook for near term earnings and 2026 estimates.

Analyst Commentary

Bearish analysts have highlighted that the modest reduction in the price target reflects growing caution around the durability of Amphastar's recent performance, particularly in light of more muted pricing and volume trends observed in the third quarter.

They note that the updated target embeds a more balanced risk reward profile, suggesting limited upside in the near term as the market waits for clearer evidence of sustainable growth and execution against long term guidance.

Bearish Takeaways

  • Bearish analysts point to softer Q3 pricing and volume trends for key drugs as a sign that near term revenue growth could be more constrained than previously assumed, weighing on valuation multiples.
  • The lack of expected major Q3 earnings surprises is seen as limiting potential catalysts, raising concern that the stock may struggle to re rate without stronger visibility into margin expansion and pipeline contribution.
  • With no significant revisions anticipated to 2026 estimates, analysts view the risk that longer term growth targets may already be fully reflected in the share price, increasing downside if execution stumbles.
  • Cautious sentiment is also tied to competitive and reimbursement pressures, which could cap future price increases and intensify scrutiny on Amphastar's ability to defend market share in its core franchises.

What's in the News

  • Completed a major share repurchase program, buying back a total of 14,106,459 shares, representing 29.68% of shares outstanding, for $369.12 million since the buyback was announced in 2016 (Key Developments)
  • In the most recent tranche from July 1, 2025 to September 30, 2025, repurchased 172,920 shares, or 0.37% of shares outstanding, for $4.85 million (Key Developments)
  • Entered a 10 year exclusive distribution agreement with Nanjing Chengong Pharmaceutical for BAQSIMI nasal powder across Mainland China, Taiwan, Hong Kong, and Macau, with Chengong responsible for regulatory approvals, post marketing trials, and minimum annual purchase commitments (Key Developments)
  • The agreement with Chengong includes a profit sharing structure above a floor price per unit, is payable in U.S. dollars, and can be terminated by either party without cause after the fourth contract year (Key Developments)
  • The distribution deal constitutes a related party transaction due to significant ownership links between Amphastar leadership and Chengong’s parent, and was approved by the company’s independent, disinterested Audit Committee members after review (Key Developments)

Valuation Changes

  • Fair Value: Unchanged at $25.00, indicating no revision to the intrinsic value estimate despite updated operating assumptions.
  • Discount Rate: Risen slightly from 6.78% to 6.96%, implying a modestly higher required return and slightly greater perceived risk.
  • Revenue Growth: Increased marginally from 2.33% to 2.37%, reflecting a small improvement in long term top line growth expectations.
  • Net Profit Margin: Risen meaningfully from 17.97% to 20.16%, signaling stronger anticipated profitability and operating leverage over time.
  • Future P/E: Fallen from 9.18x to 8.02x, suggesting a lower valuation multiple being applied to forward earnings assumptions.

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