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AnalystConsensusTarget updated the narrative for AZN

Update shared on 17 Oct 2025

Fair value Increased 2.03%
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AstraZeneca's analyst price target has been raised from £138.16 to £140.96. This reflects a modest increase as analysts highlight both expanding potential for key pipeline products and a tempered outlook on patent risk and competitive pressures in certain therapeutic areas.

Analyst Commentary

Recent street research highlights a balanced outlook for AstraZeneca, with analysts weighing the company’s pipeline growth opportunities against emerging risks in patent exposure and competitive markets.

Bullish Takeaways
  • Bullish analysts see an expanding market opportunity for pipeline products, particularly in the TTR-CM segment. Forecasts have been updated to reflect higher future revenues tied to assets like eplontersen.
  • Collaborative innovation, such as partnerships in oncology and AI-driven initiatives, is viewed as a point of differentiation. These efforts are seen as adding long-term growth drivers to AstraZeneca’s portfolio.
  • Strategic investment in U.S. manufacturing is seen as a mitigating factor against geopolitical and policy risks. This approach could benefit valuation if trade pressures intensify.
Bearish Takeaways
  • Bearish analysts express concern that the company is approaching a period of heightened patent pressure. This may limit pricing power and revenue longevity for certain therapies.
  • Lowered confidence in pipeline momentum, particularly after closer scrutiny of the breast cancer segment, raises execution risk and could temper future growth expectations.
  • Mixed quarterly results, such as underperformance in Wainua sales, introduce uncertainty into revenue forecasts and reflect challenges in meeting consensus growth targets.
  • Current share price levels are perceived as elevated relative to risk, prompting questions about upside from present valuations given sector headwinds.

What's in the News

  • President Trump announced a deal with AstraZeneca to lower consumer drug prices in the U.S. This is the second such deal with a pharmaceutical company, and includes a $50 billion commitment to invest in domestic drug manufacturing and research (Bloomberg, MSNBC).
  • Retail pharmacies and sites like GoodRx are in talks with the White House to join TrumpRx, an effort to provide Americans direct discounts on medicines. AstraZeneca is among several companies considering participation (Reuters).
  • AstraZeneca paused a planned $271 million investment in its Cambridge, U.K. research site, citing the challenging British business environment. This follows similar moves from other pharma companies (Reuters).
  • The Trump administration is advancing Medicare drug price negotiations, with new rules issued to set prices on up to 15 more drugs by 2028. This could potentially affect AstraZeneca and other major pharma firms (Bloomberg).
  • Pharmaceutical companies, including AstraZeneca, are excluded from planned tariffs on generic drugs as the administration narrows the scope of pharma levies to avoid potential shortages (Wall Street Journal).

Valuation Changes

  • Consensus Analyst Price Target has risen slightly from £138.16 to £140.96, reflecting updated market expectations.
  • Discount Rate remains unchanged at 6.82 percent. This indicates consistent risk assessment by analysts.
  • Revenue Growth is projected to increase moderately, up from 6.21 percent to 6.34 percent.
  • Net Profit Margin has declined marginally from 21.76 percent to 21.74 percent.
  • Future P/E ratio has increased modestly from 23.82x to 24.22x. This suggests a slightly higher valuation multiple on forecast earnings.

Disclaimer

AnalystConsensusTarget is a tool utilizing a Large Language Model (LLM) that ingests data on consensus price targets, forecasted revenue and earnings figures, as well as the transcripts of earnings calls to produce qualitative analysis. The narratives produced by AnalystConsensusTarget are general in nature and are based solely on analyst data and publicly-available material published by the respective companies. These scenarios are not indicative of the company's future performance and are exploratory in nature. Simply Wall St has no position in the company(s) mentioned. Simply Wall St may provide the securities issuer or related entities with website advertising services for a fee, on an arm's length basis. These relationships have no impact on the way we conduct our business, the content we host, or how our content is served to users. The price targets and estimates used are consensus data, and do not constitute a recommendation to buy or sell any stock, and they do not take account of your objectives, or your financial situation. Note that AnalystConsensusTarget's analysis may not factor in the latest price-sensitive company announcements or qualitative material.