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HVO: Positive Data From New Models Will Drive Future Demand

Update shared on 26 Nov 2025

Fair value Decreased 16%
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AnalystConsensusTarget's Fair Value
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1Y
-67.1%
7D
38.3%

Analysts have reduced their price target for hVIVO from £0.21 to £0.17. They cite slower expected revenue growth and tightening profit margins as key factors behind the adjustment.

What's in the News

  • hVIVO shared positive data from several newly developed human challenge models at major scientific conferences in October 2025, highlighting strong safety and tolerability profiles (Key Developments).
  • The company's human Metapneumovirus (hMPV) challenge model demonstrated high infection rates and robust virology results. This model is now available for clinical trials (Key Developments).
  • The introduction of the world's first commercially available Omicron (BA5) human challenge model emphasizes optimal dosing timing for post-exposure prophylaxis (Key Developments).
  • Positive results were reported from a new Respiratory Syncytial Virus B (RSV B) model, which forms a key part of a comprehensive vaccine efficacy testing platform (Key Developments).
  • hVIVO provided revenue guidance for 2026, projecting high-single digit growth driven by diversified services and normalization of Clinical Trial (HCT) activity (Key Developments).

Valuation Changes

  • Fair Value: Decreased from £0.21 to £0.17, indicating a lowered analyst valuation.
  • Discount Rate: Increased from 7.88% to 8.92%, reflecting higher perceived risk.
  • Revenue Growth: Declined significantly from 4.48% to 2.16% projected annual growth.
  • Net Profit Margin: Fell from 6.08% to 4.47%, showing expectations of reduced profitability.
  • Future P/E: More than doubled from 30.39x to 60.42x, which suggests a higher valuation relative to future earnings.

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