Upstream Bio Second Quarter 2025 Earnings: Revenues Beat Expectations, EPS Lags

August 08, 2025

Simply Wall St

NasdaqGS:UPB 1 Year Share Price vs Fair Value

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Upstream Bio (NASDAQ:UPB) Second Quarter 2025 Results

Key Financial Results

Net loss: US$40.0m (loss widened by 104% from 2Q 2024).
US$0.74 loss per share.

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earnings-and-revenue-growth — NasdaqGS:UPB Earnings and Revenue Growth August 8th 2025

All figures shown in the chart above are for the trailing 12 month (TTM) period

Upstream Bio Revenues Beat Expectations, EPS Falls Short

Revenue exceeded analyst estimates by 196%. Earnings per share (EPS) missed analyst estimates by 21%.

Looking ahead, revenue is forecast to grow 61% p.a. on average during the next 3 years, compared to a 19% growth forecast for the Biotechs industry in the US.

Performance of the American Biotechs industry.

The company's shares are up 3.5% from a week ago.

Risk Analysis

What about risks? Every company has them, and we've spotted 3 warning signs for Upstream Bio (of which 1 can't be ignored!) you should know about.

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This article by Simply Wall St is general in nature. We provide commentary based on historical data and analyst forecasts only using an unbiased methodology and our articles are not intended to be financial advice. It does not constitute a recommendation to buy or sell any stock, and does not take account of your objectives, or your financial situation. We aim to bring you long-term focused analysis driven by fundamental data. Note that our analysis may not factor in the latest price-sensitive company announcements or qualitative material. Simply Wall St has no position in any stocks mentioned.