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Beam Therapeutics NasdaqGS:BEAM Stock Report

Last Price


Market Cap







08 Aug, 2022


Company Financials +
BEAM fundamental analysis
Snowflake Score
Future Growth1/6
Past Performance0/6
Financial Health6/6

BEAM Stock Overview

Beam Therapeutics Inc., a biotechnology company, develops precision genetic medicines for patients suffering from serious diseases in the United States.

Beam Therapeutics Competitors

Price History & Performance

Summary of all time highs, changes and price drops for Beam Therapeutics
Historical stock prices
Current Share PriceUS$63.69
52 Week HighUS$116.91
52 Week LowUS$27.77
1 Month Change22.46%
3 Month Change78.00%
1 Year Change-40.45%
3 Year Changen/a
5 Year Changen/a
Change since IPO239.68%

Recent News & Updates

Aug 01

Beam drops 19% as FDA issues clinical hold on blood cancer candidate

Cambridge, Massachusetts-based Beam Therapeutics (NASDAQ:BEAM) announced on Monday that the FDA placed its Investigational New Drug (IND) application for BEAM-201, a CAR-T candidate for blood cancer, on clinical hold. Beam (BEAM) shares lost ~11% in the pre-market after the announcement. With the IND, the biotech has targeted BEAM-201 for the treatment of relapsed/refractory T-cell acute lymphoblastic leukemia (T-ALL)/T cell lymphoblastic lymphoma (T-LL). The FDA informed the decision on clinical hold last Friday via email, the company said, adding that an official letter from the agency in this regard is expected within 30 days. Beam (BEAM) submitted the IND for BEAM-201 at the end of June. A key holding of star fund manager Cathie Wood’s ARK Innovation ETF (ARKK), Beam (BEAM), drew a Market Perform rating from BMO Capital Markets recently.

Jul 10

Revisiting Beam Therapeutics Among Collaborative Catalysts

The recent 4-year partnership between Pfizer and Beam Therapeutics involves $300 million upfront to speed validation of the technology and an additional $1.05 billion in milestone payments. A recent amended agreement between Verve Therapeutics and Beam Therapeutics is a target swap that will give Beam access to Verve’s validated GalNAc-lipid nanoparticle-mediated (LNP) delivery technology. BEAM's novel CRISPR technology continues to carve a niche out in a crowded and volatile market alongside other CRISPR companies. At the time of my last publication on Beam Therapeutics (BEAM), its stock price was chopping around $82.52, and, if anything, the bear market of 2022 has only accelerated the bottoming of this gene editing leader. Recently, BMO Capital Markets initiated coverage on Beam with a "Market Perform" rating, driving the stock up >10% on the news. This came on the heels of a massive 4-year partnership announced with Pfizer (PFE) in April that delivered $300 million in upfront payments and the potential for over a billion more. While the S&P 500 and NASDAQ both remain in a technical bear market (as of writing this article), we may have seen the bottom set in for Beam and a new opportunity to accumulate a long position in anticipation of positive gene editing news in 2023. Beam Therapeutics The Beam Therapeutics gene editing platform is built to perform base edits without double stranded breaks in the target DNA, a slight variation of the classical CRISPR-cas9 system (for reference see previous articles here or other well-performed analysis by SA authors). Their portfolio has a solid foundation with flagship programs that include: BEAM-101: hematopoietic cell therapy that activates fetal hemoglobin protein for the treatment of sickle cell disease and beta-thalassemia. BEAM-102: directly correcting the hemoglobin mutation for sickle cell disease by base-editing to mimic a naturally-occurring hemoglobin variant. BEAM-201: multiplexed base editing that silences the CD7 chimeric antigen receptor T-cells for the treatment of relapsed/refractory T-cell acute lymphoblastic leukemia and T-cell lymphoblastic leukemia. Beam Therapeutics Pipeline (Beam Investor Presentation) Recent Agreements and Catalysts The Pfizer deal comes after massive obstacles for Pfizer’s own gene editing portfolio, most notably the tragic death of a patient in their Phase 1b mini-dystrophin gene therapy trial for Duchenne muscular dystrophy (DMD). Additional issues have arisen from the Roche (RHHBY) partnered hemophilia B asset that is delayed another year to 2023. Addressing these shortfalls with a step into base editing gene therapy is a natural choice for the pharmaceutical giant, captured well with their stated focus “… on in vivo base editing programs for three targets for rare genetic diseases of the liver, muscle and central nervous system.” In all, Beam receives an upfront payment of $300M, potential milestone payments up to $1.35B, and eligibility to receive royalties on global net sales for each licensed program. In addition, Beam will conduct research activities through development candidate selection for three undisclosed targets, one each in liver, muscle, and CNS, at which point Pfizer may opt in to exclusive, worldwide licenses to each development candidate (and be responsible for all development activities, potential regulatory approvals, commercialization, etc). We have a strong history in developing gene replacement therapies for rare diseases, and we see this collaboration with Beam as an opportunity to advance the next generation of gene editing therapies – an exciting scientific frontier – potentially leading to transformation for people living with rare genetic diseases. Mikael Dolsten, M.D., Ph.D., Chief Scientific Officer and President, Worldwide Research, Development and Medical of Pfizer. Surprisingly, the recent Verve-Beam agreement amendments didn’t warrant a press release, but they deserve mention here. The amendments grant Beam the target-by-target option to license Verve Therapeutics’ (VERV) GalNAc-LNP delivery technology for base editing machinery delivery, as well as additional rights to a 35% expense and profit share for an additional liver-mediated, cardiovascular target. Another big reveal in the new agreement is Verve granting Beam an exclusive, fully paid license relating to an undisclosed preclinical program being developed by Verve. All this considered, it reads as another shot on goal for the Beam Therapeutics team, with another biotech falling in line with the potential of genetic base editing.

Shareholder Returns

BEAMUS BiotechsUS Market

Return vs Industry: BEAM underperformed the US Biotechs industry which returned -24.5% over the past year.

Return vs Market: BEAM underperformed the US Market which returned -12.9% over the past year.

Price Volatility

Is BEAM's price volatile compared to industry and market?
BEAM volatility
BEAM Average Weekly Movement14.4%
Biotechs Industry Average Movement12.9%
Market Average Movement7.9%
10% most volatile stocks in US Market17.1%
10% least volatile stocks in US Market3.2%

Stable Share Price: BEAM is more volatile than 75% of US stocks over the past 3 months, typically moving +/- 14% a week.

Volatility Over Time: BEAM's weekly volatility (14%) has been stable over the past year, but is still higher than 75% of US stocks.

About the Company

2017394John Evans

Beam Therapeutics Inc., a biotechnology company, develops precision genetic medicines for patients suffering from serious diseases in the United States. The company is developing BEAM-101 for the treatment of sickle cell disease and beta thalassemia; BEAM-102 for the treatment of sickle cell disease; and BEAM-201, an allogeneic chimeric antigen receptor T cell for the treatment of relapsed/refractory T-cell acute lymphoblastic leukemia; and BEAM-301, a liver-targeted development candidate for the treatment of patients with Glycogen Storage Disease Type Ia. It also develops therapies for alpha-1 antitrypsin deficiency; ocular diseases; and other liver, muscle, and central nervous system disorders.

Beam Therapeutics Fundamentals Summary

How do Beam Therapeutics's earnings and revenue compare to its market cap?
BEAM fundamental statistics
Market CapUS$4.38b
Earnings (TTM)-US$238.29m
Revenue (TTM)US$60.27m


P/S Ratio


P/E Ratio

Earnings & Revenue

Key profitability statistics from the latest earnings report
BEAM income statement (TTM)
Cost of RevenueUS$99.30m
Gross Profit-US$39.03m
Other ExpensesUS$199.26m

Last Reported Earnings

Mar 31, 2022

Next Earnings Date


Earnings per share (EPS)-3.47
Gross Margin-64.76%
Net Profit Margin-395.37%
Debt/Equity Ratio0%

How did BEAM perform over the long term?

See historical performance and comparison
We’ve recently updated our valuation analysis.


Is BEAM undervalued compared to its fair value, analyst forecasts and its price relative to the market?

Valuation Score


Valuation Score 1/6

  • Price-To-Book vs Peers

  • Price-To-Book vs Industry

  • Price-To-Book vs Fair Ratio

  • Below Fair Value

  • Significantly Below Fair Value

  • Analyst Forecast

Key Valuation Metric

Which metric is best to use when looking at relative valuation for BEAM?

Other financial metrics that can be useful for relative valuation.

BEAM key valuation metrics and ratios. From Price to Earnings, Price to Sales and Price to Book to Price to Earnings Growth Ratio, Enterprise Value and EBITDA.
Key Statistics
Enterprise Value/Revenue54.8x
Enterprise Value/EBITDA-31.8x
PEG Ration/a

Price to Book Ratio vs Peers

How does BEAM's PB Ratio compare to its peers?

BEAM PB Ratio vs Peers
The above table shows the PB ratio for BEAM vs its peers. Here we also display the market cap and forecasted growth for additional consideration.
CompanyPBEstimated GrowthMarket Cap
Peer Average472.9x
KRTX Karuna Therapeutics
VIR Vir Biotechnology
VSBC VitaSpring Biomedical
NVAX Novavax
BEAM Beam Therapeutics

Price-To-Book vs Peers: BEAM is good value based on its Price-To-Book Ratio (5.3x) compared to the peer average (472.9x).

Price to Earnings Ratio vs Industry

How does BEAM's PE Ratio compare vs other companies in the US Biotechs Industry?

Price-To-Book vs Industry: BEAM is expensive based on its Price-To-Book Ratio (5.3x) compared to the US Biotechs industry average (1.8x)

Price to Book Ratio vs Fair Ratio

What is BEAM's PB Ratio compared to its Fair PB Ratio? This is the expected PB Ratio taking into account the company's forecast earnings growth, profit margins and other risk factors.

BEAM PB Ratio vs Fair Ratio.
Fair Ratio
Current PB Ratio5.3x
Fair PB Ration/a

Price-To-Book vs Fair Ratio: Insufficient data to calculate BEAM's Price-To-Book Fair Ratio for valuation analysis.

Share Price vs Fair Value

What is the Fair Price of BEAM when looking at its future cash flows? For this estimate we use a Discounted Cash Flow model.

Below Fair Value: Insufficient data to calculate BEAM's fair value for valuation analysis.

Significantly Below Fair Value: Insufficient data to calculate BEAM's fair value for valuation analysis.

Analyst Price Targets

What is the analyst 12-month forecast and do we have any statistical confidence in the consensus price target?

Analyst Forecast: Target price is more than 20% higher than the current share price, but analysts are not within a statistically confident range of agreement.

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Future Growth

How is Beam Therapeutics forecast to perform in the next 1 to 3 years based on estimates from 12 analysts?

Future Growth Score


Future Growth Score 1/6

  • Earnings vs Savings Rate

  • Earnings vs Market

  • High Growth Earnings

  • Revenue vs Market

  • High Growth Revenue

  • Future ROE


Forecasted annual earnings growth

Earnings and Revenue Growth Forecasts

Analyst Future Growth Forecasts

Earnings vs Savings Rate: BEAM is forecast to remain unprofitable over the next 3 years.

Earnings vs Market: BEAM is forecast to remain unprofitable over the next 3 years.

High Growth Earnings: BEAM is forecast to remain unprofitable over the next 3 years.

Revenue vs Market: BEAM's revenue (17.7% per year) is forecast to grow faster than the US market (8% per year).

High Growth Revenue: BEAM's revenue (17.7% per year) is forecast to grow slower than 20% per year.

Earnings per Share Growth Forecasts

Future Return on Equity

Future ROE: BEAM is forecast to be unprofitable in 3 years.

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Past Performance

How has Beam Therapeutics performed over the past 5 years?

Past Performance Score


Past Performance Score 0/6

  • Quality Earnings

  • Growing Profit Margin

  • Earnings Trend

  • Accelerating Growth

  • Earnings vs Industry

  • High ROE


Historical annual earnings growth

Earnings and Revenue History

Quality Earnings: BEAM is currently unprofitable.

Growing Profit Margin: BEAM is currently unprofitable.

Past Earnings Growth Analysis

Earnings Trend: BEAM is unprofitable, and losses have increased over the past 5 years at a rate of 45.2% per year.

Accelerating Growth: Unable to compare BEAM's earnings growth over the past year to its 5-year average as it is currently unprofitable

Earnings vs Industry: BEAM is unprofitable, making it difficult to compare its past year earnings growth to the Biotechs industry (40.8%).

Return on Equity

High ROE: BEAM has a negative Return on Equity (-28.74%), as it is currently unprofitable.

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Financial Health

How is Beam Therapeutics's financial position?

Financial Health Score


Financial Health Score 6/6

  • Short Term Liabilities

  • Long Term Liabilities

  • Debt Level

  • Reducing Debt

  • Stable Cash Runway

  • Forecast Cash Runway

Financial Position Analysis

Short Term Liabilities: BEAM's short term assets ($1.2B) exceed its short term liabilities ($218.8M).

Long Term Liabilities: BEAM's short term assets ($1.2B) exceed its long term liabilities ($405.5M).

Debt to Equity History and Analysis

Debt Level: BEAM is debt free.

Reducing Debt: BEAM has not had any debt for past 5 years.

Balance Sheet

Cash Runway Analysis

For companies that have on average been loss making in the past we assess whether they have at least 1 year of cash runway.

Stable Cash Runway: Whilst unprofitable BEAM has sufficient cash runway for more than 3 years if it maintains its current positive free cash flow level.

Forecast Cash Runway: BEAM is unprofitable but has sufficient cash runway for more than 3 years, even with free cash flow being positive and shrinking by 7.5% per year.

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What is Beam Therapeutics's current dividend yield, its reliability and sustainability?

Dividend Score


Dividend Score 0/6

  • Notable Dividend

  • High Dividend

  • Stable Dividend

  • Growing Dividend

  • Earnings Coverage

  • Cash Flow Coverage

Dividend Yield vs Market

Notable Dividend: Unable to evaluate BEAM's dividend yield against the bottom 25% of dividend payers, as the company has not reported any recent payouts.

High Dividend: Unable to evaluate BEAM's dividend yield against the top 25% of dividend payers, as the company has not reported any recent payouts.

Stability and Growth of Payments

Stable Dividend: Insufficient data to determine if BEAM's dividends per share have been stable in the past.

Growing Dividend: Insufficient data to determine if BEAM's dividend payments have been increasing.

Earnings Payout to Shareholders

Earnings Coverage: Insufficient data to calculate payout ratio to determine if its dividend payments are covered by earnings.

Cash Payout to Shareholders

Cash Flow Coverage: Unable to calculate sustainability of dividends as BEAM has not reported any payouts.

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How experienced are the management team and are they aligned to shareholders interests?


Average management tenure


John Evans (44 yo)





Mr. John M. Evans is a Director at Prime Medicine, Inc. He serves as Chief Executive Officer and Director at Beam Therapeutics Inc. since January 2018 and served as its President since January 2018 until J...

CEO Compensation Analysis

Compensation vs Market: John's total compensation ($USD13.91M) is above average for companies of similar size in the US market ($USD6.58M).

Compensation vs Earnings: John's compensation has increased whilst the company is unprofitable.

Leadership Team

Experienced Management: BEAM's management team is considered experienced (3.9 years average tenure).

Board Members

Experienced Board: BEAM's board of directors are considered experienced (3.3 years average tenure).


Who are the major shareholders and have insiders been buying or selling?

Insider Trading Volume

Insider Buying: Insufficient data to determine if insiders have bought more shares than they have sold in the past 3 months.

Recent Insider Transactions

Ownership Breakdown

Dilution of Shares: Shareholders have been diluted in the past year, with total shares outstanding growing by 11.8%.

Top Shareholders

Company Information

Beam Therapeutics Inc.'s employee growth, exchange listings and data sources

Key Information

  • Name: Beam Therapeutics Inc.
  • Ticker: BEAM
  • Exchange: NasdaqGS
  • Founded: 2017
  • Industry: Biotechnology
  • Sector: Pharmaceuticals & Biotech
  • Implied Market Cap: US$4.377b
  • Shares outstanding: 68.72m
  • Website:

Number of Employees


  • Beam Therapeutics Inc.
  • 238 Main Street
  • 9th Floor
  • Cambridge
  • Massachusetts
  • 2142
  • United States


Company Analysis and Financial Data Status

All financial data provided by Standard & Poor's Capital IQ.
DataLast Updated (UTC time)
Company Analysis2022/08/08 00:00
End of Day Share Price2022/08/08 00:00
Annual Earnings2021/12/31

Unless specified all financial data is based on a yearly period but updated quarterly. This is known as Trailing Twelve Month (TTM) or Last Twelve Month (LTM) Data. Learn more here.