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BioCryst Pharmaceuticals NasdaqGS:BCRX Stock Report

Last Price


Market Cap







18 Aug, 2022


Company Financials +
BCRX fundamental analysis
Snowflake Score
Future Growth5/6
Past Performance0/6
Financial Health1/6

BCRX Stock Overview

BioCryst Pharmaceuticals, Inc., a biotechnology company, discovers novel, oral, and small-molecule medicines.

BioCryst Pharmaceuticals Competitors

Price History & Performance

Summary of all time highs, changes and price drops for BioCryst Pharmaceuticals
Historical stock prices
Current Share PriceUS$14.33
52 Week HighUS$19.99
52 Week LowUS$7.61
1 Month Change21.13%
3 Month Change57.47%
1 Year Change0.63%
3 Year Change457.59%
5 Year Change196.69%
Change since IPO120.46%

Recent News & Updates

Aug 18

BioCryst Orladeyo gets approval in Saudi Arabia to prevent hereditary angioedema attacks

The Saudi Food and Drug Authority (SFDA) approved BioCryst Pharmaceuticals' (NASDAQ:BCRX) oral medicine Orladeyo (berotralstat) to prevent attacks of hereditary angioedema (HAE) in patients 12 years and older. In September 2021, BioCryst signed a distribution agreement with Dubai-based NewBridge Pharmaceuticals, which also covers the Gulf Cooperation Council (GCC) and Iraq. "This marks the second market in the MENA region in which ORLADEYO has been approved for patients living with HAE, building on the approval in the UAE last year," said NewBridge President and CEO Joe Henein. The drug is already approved in the U.S., Canada, and Switzerland among other places. HAE is a disorder characterized by recurrent episodes (attacks) of severe swelling of the skin and mucous membranes.

Aug 03

BioCryst Pharmaceuticals Q2 2022 Earnings Preview

BioCryst Pharmaceuticals (NASDAQ:BCRX) is scheduled to announce Q2 earnings results on Thursday, August 4th, before market open. The consensus EPS Estimate is -$0.35 (-45.8% Y/Y) and the consensus Revenue Estimate is $63.83M (+27.7% Y/Y). Over the last 1 year, BCRX has beaten EPS estimates 25% of the time and has beaten revenue estimates 50% of the time. Over the last 3 months, EPS estimates have seen 4 upward revisions and 3 downward. Revenue estimates have seen 5 upward revisions and 5 downward.

Shareholder Returns

BCRXUS BiotechsUS Market

Return vs Industry: BCRX exceeded the US Biotechs industry which returned -23% over the past year.

Return vs Market: BCRX exceeded the US Market which returned -9% over the past year.

Price Volatility

Is BCRX's price volatile compared to industry and market?
BCRX volatility
BCRX Average Weekly Movement10.0%
Biotechs Industry Average Movement12.4%
Market Average Movement7.6%
10% most volatile stocks in US Market17.1%
10% least volatile stocks in US Market3.1%

Stable Share Price: BCRX is not significantly more volatile than the rest of US stocks over the past 3 months, typically moving +/- 10% a week.

Volatility Over Time: BCRX's weekly volatility (10%) has been stable over the past year.

About the Company

1986358Jon Stonehouse

BioCryst Pharmaceuticals, Inc., a biotechnology company, discovers novel, oral, and small-molecule medicines. The company markets peramivir injection, an intravenous neuraminidase inhibitor for the treatment of acute uncomplicated influenza under the RAPIVAB, RAPIACTA, and PERAMIFLU names; and ORLADEYO, an oral serine protease inhibitor to treat hereditary angioedema. It is also developing BCX9930, an oral factor D inhibitor, which is in Phase II clinical trial for complement-mediated diseases; BCX9250, an oral activin receptor-like kinase-2 inhibitor that is in Phase I clinical trial to treat fibrodysplasia ossificans progressiva; and Galidesivir, a RNA dependent-RNA polymerase inhibitor, which is in Phase I clinical trial to treat various RNA viruses, including Marburg, Yellow Fever, Ebola, and Zika.

BioCryst Pharmaceuticals Fundamentals Summary

How do BioCryst Pharmaceuticals's earnings and revenue compare to its market cap?
BCRX fundamental statistics
Market CapUS$2.66b
Earnings (TTM)-US$209.63m
Revenue (TTM)US$203.61m


P/S Ratio


P/E Ratio

Earnings & Revenue

Key profitability statistics from the latest earnings report
BCRX income statement (TTM)
Cost of RevenueUS$242.37m
Gross Profit-US$38.76m
Other ExpensesUS$170.87m

Last Reported Earnings

Jun 30, 2022

Next Earnings Date


Earnings per share (EPS)-1.13
Gross Margin-19.04%
Net Profit Margin-102.96%
Debt/Equity Ratio-291.8%

How did BCRX perform over the long term?

See historical performance and comparison
We’ve recently updated our valuation analysis.


Is BCRX undervalued compared to its fair value, analyst forecasts and its price relative to the market?

Valuation Score


Valuation Score 4/6

  • Price-To-Sales vs Peers

  • Price-To-Sales vs Industry

  • Price-To-Sales vs Fair Ratio

  • Below Fair Value

  • Significantly Below Fair Value

  • Analyst Forecast

Key Valuation Metric

Which metric is best to use when looking at relative valuation for BCRX?

Other financial metrics that can be useful for relative valuation.

BCRX key valuation metrics and ratios. From Price to Earnings, Price to Sales and Price to Book to Price to Earnings Growth Ratio, Enterprise Value and EBITDA.
Key Statistics
Enterprise Value/Revenue14.1x
Enterprise Value/EBITDA-16x
PEG Ration/a

Price to Sales Ratio vs Peers

How does BCRX's PS Ratio compare to its peers?

BCRX PS Ratio vs Peers
The above table shows the PS ratio for BCRX vs its peers. Here we also display the market cap and forecasted growth for additional consideration.
CompanyPSEstimated GrowthMarket Cap
Peer Average16.8x
FATE Fate Therapeutics
NVAX Novavax
GBT Global Blood Therapeutics
BCRX BioCryst Pharmaceuticals

Price-To-Sales vs Peers: BCRX is good value based on its Price-To-Sales Ratio (13.1x) compared to the peer average (16.8x).

Price to Earnings Ratio vs Industry

How does BCRX's PE Ratio compare vs other companies in the US Biotechs Industry?

Price-To-Sales vs Industry: BCRX is good value based on its Price-To-Sales Ratio (13.1x) compared to the US Biotechs industry average (15.8x)

Price to Sales Ratio vs Fair Ratio

What is BCRX's PS Ratio compared to its Fair PS Ratio? This is the expected PS Ratio taking into account the company's forecast earnings growth, profit margins and other risk factors.

BCRX PS Ratio vs Fair Ratio.
Fair Ratio
Current PS Ratio13.1x
Fair PS Ratio4.6x

Price-To-Sales vs Fair Ratio: BCRX is expensive based on its Price-To-Sales Ratio (13.1x) compared to the estimated Fair Price-To-Sales Ratio (4.6x).

Share Price vs Fair Value

What is the Fair Price of BCRX when looking at its future cash flows? For this estimate we use a Discounted Cash Flow model.

Below Fair Value: BCRX ($14.33) is trading below our estimate of fair value ($67.99)

Significantly Below Fair Value: BCRX is trading below fair value by more than 20%.

Analyst Price Targets

What is the analyst 12-month forecast and do we have any statistical confidence in the consensus price target?

Analyst Forecast: Target price is more than 20% higher than the current share price, but analysts are not within a statistically confident range of agreement.

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Future Growth

How is BioCryst Pharmaceuticals forecast to perform in the next 1 to 3 years based on estimates from 9 analysts?

Future Growth Score


Future Growth Score 5/6

  • Earnings vs Savings Rate

  • Earnings vs Market

  • High Growth Earnings

  • Revenue vs Market

  • High Growth Revenue

  • Future ROE


Forecasted annual earnings growth

Earnings and Revenue Growth Forecasts

Analyst Future Growth Forecasts

Earnings vs Savings Rate: BCRX is forecast to become profitable over the next 3 years, which is considered faster growth than the savings rate (1.9%).

Earnings vs Market: BCRX is forecast to become profitable over the next 3 years, which is considered above average market growth.

High Growth Earnings: BCRX is expected to become profitable in the next 3 years.

Revenue vs Market: BCRX's revenue (23.4% per year) is forecast to grow faster than the US market (7.8% per year).

High Growth Revenue: BCRX's revenue (23.4% per year) is forecast to grow faster than 20% per year.

Earnings per Share Growth Forecasts

Future Return on Equity

Future ROE: Insufficient data to determine if BCRX's Return on Equity is forecast to be high in 3 years time

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Past Performance

How has BioCryst Pharmaceuticals performed over the past 5 years?

Past Performance Score


Past Performance Score 0/6

  • Quality Earnings

  • Growing Profit Margin

  • Earnings Trend

  • Accelerating Growth

  • Earnings vs Industry

  • High ROE


Historical annual earnings growth

Earnings and Revenue History

Quality Earnings: BCRX is currently unprofitable.

Growing Profit Margin: BCRX is currently unprofitable.

Past Earnings Growth Analysis

Earnings Trend: BCRX is unprofitable, and losses have increased over the past 5 years at a rate of 26.2% per year.

Accelerating Growth: Unable to compare BCRX's earnings growth over the past year to its 5-year average as it is currently unprofitable

Earnings vs Industry: BCRX is unprofitable, making it difficult to compare its past year earnings growth to the Biotechs industry (24.5%).

Return on Equity

High ROE: BCRX's liabilities exceed its assets, so it is difficult to calculate its Return on Equity.

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Financial Health

How is BioCryst Pharmaceuticals's financial position?

Financial Health Score


Financial Health Score 1/6

  • Short Term Liabilities

  • Long Term Liabilities

  • Debt Level

  • Reducing Debt

  • Stable Cash Runway

  • Forecast Cash Runway

Financial Position Analysis

Short Term Liabilities: BCRX has negative shareholder equity, which is a more serious situation than short term assets not covering short term liabilities.

Long Term Liabilities: BCRX has negative shareholder equity, which is a more serious situation than short term assets not covering long term liabilities.

Debt to Equity History and Analysis

Debt Level: BCRX has negative shareholder equity, which is a more serious situation than a high debt level.

Reducing Debt: BCRX's has negative shareholder equity, so we do not need to check if its debt has reduced over time.

Balance Sheet

Cash Runway Analysis

For companies that have on average been loss making in the past we assess whether they have at least 1 year of cash runway.

Stable Cash Runway: BCRX has sufficient cash runway for more than a year based on its current free cash flow.

Forecast Cash Runway: Insufficient data to determine if BCRX has enough cash runway if its free cash flow continues to grow or shrink based on historical rates.

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What is BioCryst Pharmaceuticals's current dividend yield, its reliability and sustainability?

Dividend Score


Dividend Score 0/6

  • Notable Dividend

  • High Dividend

  • Stable Dividend

  • Growing Dividend

  • Earnings Coverage

  • Cash Flow Coverage

Dividend Yield vs Market

Notable Dividend: Unable to evaluate BCRX's dividend yield against the bottom 25% of dividend payers, as the company has not reported any recent payouts.

High Dividend: Unable to evaluate BCRX's dividend yield against the top 25% of dividend payers, as the company has not reported any recent payouts.

Stability and Growth of Payments

Stable Dividend: Insufficient data to determine if BCRX's dividends per share have been stable in the past.

Growing Dividend: Insufficient data to determine if BCRX's dividend payments have been increasing.

Earnings Payout to Shareholders

Earnings Coverage: Insufficient data to calculate payout ratio to determine if its dividend payments are covered by earnings.

Cash Payout to Shareholders

Cash Flow Coverage: Unable to calculate sustainability of dividends as BCRX has not reported any payouts.

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How experienced are the management team and are they aligned to shareholders interests?


Average management tenure


Jon Stonehouse (61 yo)





Mr. Jon P. Stonehouse has been the Chief Executive Officer and Executive Director of BioCryst Pharmaceuticals, Inc. at Shionogi & Co., Ltd. since joining on January 8, 2007 and also has been its President...

CEO Compensation Analysis

Compensation vs Market: Jon's total compensation ($USD7.06M) is about average for companies of similar size in the US market ($USD6.64M).

Compensation vs Earnings: Jon's compensation has increased whilst the company is unprofitable.

Leadership Team

Experienced Management: BCRX's management team is considered experienced (2.6 years average tenure).

Board Members

Experienced Board: BCRX's board of directors are considered experienced (3.6 years average tenure).


Who are the major shareholders and have insiders been buying or selling?

Insider Trading Volume

Insider Buying: Insufficient data to determine if insiders have bought more shares than they have sold in the past 3 months.

Recent Insider Transactions

Ownership Breakdown

Dilution of Shares: Shareholders have been diluted in the past year, with total shares outstanding growing by 4%.

Top Shareholders

Company Information

BioCryst Pharmaceuticals, Inc.'s employee growth, exchange listings and data sources

Key Information

  • Name: BioCryst Pharmaceuticals, Inc.
  • Ticker: BCRX
  • Exchange: NasdaqGS
  • Founded: 1986
  • Industry: Biotechnology
  • Sector: Pharmaceuticals & Biotech
  • Implied Market Cap: US$2.665b
  • Shares outstanding: 185.95m
  • Website:

Number of Employees


  • BioCryst Pharmaceuticals, Inc.
  • 4505 Emperor Boulevard
  • Suite 200
  • Durham
  • North Carolina
  • 27703
  • United States


Company Analysis and Financial Data Status

All financial data provided by Standard & Poor's Capital IQ.
DataLast Updated (UTC time)
Company Analysis2022/08/18 00:00
End of Day Share Price2022/08/18 00:00
Annual Earnings2021/12/31

Unless specified all financial data is based on a yearly period but updated quarterly. This is known as Trailing Twelve Month (TTM) or Last Twelve Month (LTM) Data. Learn more here.