TransMedics (TMDX): Evaluating Valuation After Strong Year-to-Date Share Price Gains

Simply Wall St

TransMedics Group (TMDX) has caught investor attention after trading higher by nearly 1% today. The company has seen substantial returns this year, which has sparked new conversation around its valuation and growth potential.

See our latest analysis for TransMedics Group.

Momentum is clearly building for TransMedics Group, with a 1-day share price gain of 0.38% and a notable 120% price return year-to-date. Over the past year, the total shareholder return has reached 71.85%, which highlights strong market confidence and excitement about growth prospects.

If the recent run-up in TransMedics Group has you curious about what else is on the move in medtech, it's a great moment to discover See the full list for free.

With shares now well above analyst targets and years of impressive returns, the key question is whether TransMedics is still undervalued or if investors have already accounted for all the company’s future growth potential.

Most Popular Narrative: 3% Overvalued

The narrative fair value for TransMedics Group stands at $141.91, compared to a last close of $146.31. This gap, though small, signals skepticism about further short-term upside and puts a sharper focus on the catalysts and expectations that drive this valuation.

Expansion into new organ types (notably kidney) and next-generation product launches (Gen 3 OCS platforms for heart, lung, and liver) are expected to materially grow TransMedics' total addressable market, improve product mix, and support higher average selling prices. This is anticipated to benefit earnings and longer-term net margins.

Read the complete narrative.

Curious what powers this ambitious narrative? There is a bold bet on the future of high-tech transplant devices and major market expansion. Want to see the revenue, profit, and valuation changes that have analysts divided? Click to uncover the quantitative story behind the buzz.

Result: Fair Value of $141.91 (OVERVALUED)

Have a read of the narrative in full and understand what's behind the forecasts.

However, TransMedics still faces challenges, such as reliance on successful clinical trials and the risk that international expansion may not deliver as expected.

Find out about the key risks to this TransMedics Group narrative.

Another View: Discounted Cash Flow Says Undervalued

While the narrative-driven fair value sees TransMedics Group as modestly overvalued, our DCF model presents a very different perspective. Using conservative assumptions about future cash flows, the DCF approach sets fair value much higher. This suggests shares are trading significantly below their intrinsic worth.

Look into how the SWS DCF model arrives at its fair value.

TMDX Discounted Cash Flow as at Dec 2025

Simply Wall St performs a discounted cash flow (DCF) on every stock in the world every day (check out TransMedics Group for example). We show the entire calculation in full. You can track the result in your watchlist or portfolio and be alerted when this changes, or use our stock screener to discover 920 undervalued stocks based on their cash flows. If you save a screener we even alert you when new companies match - so you never miss a potential opportunity.

Build Your Own TransMedics Group Narrative

If you have your own perspective or want to dig into the numbers yourself, you can shape a custom narrative in just a few minutes. Do it your way

A good starting point is our analysis highlighting 3 key rewards investors are optimistic about regarding TransMedics Group.

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This article by Simply Wall St is general in nature. We provide commentary based on historical data and analyst forecasts only using an unbiased methodology and our articles are not intended to be financial advice. It does not constitute a recommendation to buy or sell any stock, and does not take account of your objectives, or your financial situation. We aim to bring you long-term focused analysis driven by fundamental data. Note that our analysis may not factor in the latest price-sensitive company announcements or qualitative material. Simply Wall St has no position in any stocks mentioned.

Valuation is complex, but we're here to simplify it.

Discover if TransMedics Group might be undervalued or overvalued with our detailed analysis, featuring fair value estimates, potential risks, dividends, insider trades, and its financial condition.

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