We're Not Very Worried About Modalis Therapeutics' (TSE:4883) Cash Burn Rate

Even when a business is losing money, it's possible for shareholders to make money if they buy a good business at the right price. For example, although software-as-a-service business Salesforce.com lost money for years while it grew recurring revenue, if you held shares since 2005, you'd have done very well indeed. But while history lauds those rare successes, those that fail are often forgotten; who remembers Pets.com?

So should Modalis Therapeutics (TSE:4883) shareholders be worried about its cash burn? For the purpose of this article, we'll define cash burn as the amount of cash the company is spending each year to fund its growth (also called its negative free cash flow). Let's start with an examination of the business' cash, relative to its cash burn.

Advertisement

How Long Is Modalis Therapeutics' Cash Runway?

A cash runway is defined as the length of time it would take a company to run out of money if it kept spending at its current rate of cash burn. In March 2025, Modalis Therapeutics had JP¥3.6b in cash, and was debt-free. Looking at the last year, the company burnt through JP¥1.4b. So it had a cash runway of about 2.5 years from March 2025. Arguably, that's a prudent and sensible length of runway to have. Depicted below, you can see how its cash holdings have changed over time.

debt-equity-history-analysis
TSE:4883 Debt to Equity History June 14th 2025

See our latest analysis for Modalis Therapeutics

How Is Modalis Therapeutics' Cash Burn Changing Over Time?

Modalis Therapeutics didn't record any revenue over the last year, indicating that it's an early stage company still developing its business. Nonetheless, we can still examine its cash burn trajectory as part of our assessment of its cash burn situation. Even though it doesn't get us excited, the 36% reduction in cash burn year on year does suggest the company can continue operating for quite some time. Admittedly, we're a bit cautious of Modalis Therapeutics due to its lack of significant operating revenues. We prefer most of the stocks on this list of stocks that analysts expect to grow.

How Easily Can Modalis Therapeutics Raise Cash?

Even though it has reduced its cash burn recently, shareholders should still consider how easy it would be for Modalis Therapeutics to raise more cash in the future. Issuing new shares, or taking on debt, are the most common ways for a listed company to raise more money for its business. Commonly, a business will sell new shares in itself to raise cash and drive growth. We can compare a company's cash burn to its market capitalisation to get a sense for how many new shares a company would have to issue to fund one year's operations.

Modalis Therapeutics' cash burn of JP¥1.4b is about 22% of its JP¥6.6b market capitalisation. That's fairly notable cash burn, so if the company had to sell shares to cover the cost of another year's operations, shareholders would suffer some costly dilution.

Is Modalis Therapeutics' Cash Burn A Worry?

On this analysis of Modalis Therapeutics' cash burn, we think its cash runway was reassuring, while its cash burn relative to its market cap has us a bit worried. Considering all the factors discussed in this article, we're not overly concerned about the company's cash burn, although we do think shareholders should keep an eye on how it develops. Taking a deeper dive, we've spotted 5 warning signs for Modalis Therapeutics you should be aware of, and 4 of them make us uncomfortable.

Of course Modalis Therapeutics may not be the best stock to buy. So you may wish to see this free collection of companies boasting high return on equity, or this list of stocks with high insider ownership.

New: Manage All Your Stock Portfolios in One Place

We've created the ultimate portfolio companion for stock investors, and it's free.

• Connect an unlimited number of Portfolios and see your total in one currency
• Be alerted to new Warning Signs or Risks via email or mobile
• Track the Fair Value of your stocks

Try a Demo Portfolio for Free

Have feedback on this article? Concerned about the content? Get in touch with us directly. Alternatively, email editorial-team (at) simplywallst.com.

This article by Simply Wall St is general in nature. We provide commentary based on historical data and analyst forecasts only using an unbiased methodology and our articles are not intended to be financial advice. It does not constitute a recommendation to buy or sell any stock, and does not take account of your objectives, or your financial situation. We aim to bring you long-term focused analysis driven by fundamental data. Note that our analysis may not factor in the latest price-sensitive company announcements or qualitative material. Simply Wall St has no position in any stocks mentioned.

About TSE:4883

Modalis Therapeutics

Engages in the research and development of therapeutics to treat patients with serious genetic disorders.

Flawless balance sheet with slight risk.

Advertisement

Weekly Picks

VA
valuebull
GOAI logo
valuebull on Eva Live ·

Is this the AI replacing marketing professionals?

Fair Value:US$7.4346.7% undervalued
13 users have followed this narrative
0 users have commented on this narrative
3 users have liked this narrative
ZA
PME logo
ZayaanS on Pro Medicus ·

Pro Medicus: The Market Is Confusing a Lumpy Quarter With a Broken Business

Fair Value:AU$196.7838.3% undervalued
26 users have followed this narrative
4 users have commented on this narrative
18 users have liked this narrative
ST
WBD logo
SteveGruber on Warner Bros. Discovery ·

The Rising Deal Risk That Helped Sink Netflix’s $72 Billion Bid for Warner Bros. Discovery  

Fair Value:US$18.1753.8% overvalued
5 users have followed this narrative
1 users have commented on this narrative
3 users have liked this narrative
PD
VRT logo
pdixit1 on Vertiv Holdings Co ·

The Infrastructure AI Cannot Be Built Without

Fair Value:US$408.6438.5% undervalued
31 users have followed this narrative
3 users have commented on this narrative
13 users have liked this narrative

Updated Narratives

AN
andre_santos
O logo
andre_santos on Realty Income ·

Realty Income - A Fundamental and Historical Valuation

Fair Value:US$73.4610.2% undervalued
29 users have followed this narrative
0 users have commented on this narrative
0 users have liked this narrative
HP
MSFT logo
HpN on Microsoft ·

A Structured Counter‑Analysis of "The Leaking Dreadnought"

Fair Value:US$509.8220.5% undervalued
1 users have followed this narrative
0 users have commented on this narrative
0 users have liked this narrative
VE
Vestra
GOOGL logo
Vestra on Alphabet ·

Alphabet Inc. (GOOG): The Gemini Era – Consolidating AI Dominance in 2026.

Fair Value:US$35514.6% undervalued
4 users have followed this narrative
0 users have commented on this narrative
0 users have liked this narrative

Popular Narratives

DA
davidlsander
UBI logo
davidlsander on Ubisoft Entertainment ·

Is Ubisoft the Market’s Biggest Pricing Error? Why Forensic Value Points to €33 Per Share

Fair Value:€33.888.0% undervalued
65 users have followed this narrative
5 users have commented on this narrative
28 users have liked this narrative
KA
NU logo
kabz2342 on Nu Holdings ·

Nu holdings will continue to disrupt the South American banking market

Fair Value:US$64.376.7% undervalued
48 users have followed this narrative
3 users have commented on this narrative
27 users have liked this narrative
AN
AnalystConsensusTarget
MSFT logo
AnalystConsensusTarget on Microsoft ·

Analyst Commentary Highlights Microsoft AI Momentum and Upward Valuation Amid Growth and Competitive Risks

Fair Value:US$59632.0% undervalued
1299 users have followed this narrative
2 users have commented on this narrative
10 users have liked this narrative