How Investors May Respond To PeptiDream (TSE:4587) Advancing Prostate Cancer Radiopharmaceutical Trial in Japan

Simply Wall St
  • Curium Group, together with PeptiDream Inc. and PDRadiopharma Inc., recently initiated a registrational Phase 2 clinical trial in Japan for 64Cu-PSMA-I&T, a PET radiopharmaceutical aimed at prostate cancer diagnosis.
  • This move highlights the collaboration's ambition to advance both diagnostic and therapeutic radiopharmaceutical solutions for prostate cancer, leveraging global clinical data and developing a companion therapeutic candidate, 177Lu-PSMA-I&T.
  • We'll explore how the advancement of PeptiDream's prostate cancer radiopharmaceutical programs shapes its long-term investment outlook.

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PeptiDream Investment Narrative Recap

To be a shareholder in PeptiDream, you need to believe in the company's ability to convert innovation in radiopharmaceuticals and peptide therapeutics into significant and recurring revenues, while managing capital-intensive R&D and competitive pressures. The initiation of the Phase 2 trial for 64Cu-PSMA-I&T in prostate cancer is positive for visibility, but it does not fundamentally change that the main short-term catalyst remains the closure of large out-licensing deals, particularly for myostatin, nor does it remove the risk of ongoing earnings and cash burn.

Of recent announcements, the expanded collaboration with Novartis stands out, given its potential for substantial upfront and milestone payments. This partnership is especially relevant as it underscores PeptiDream's ability to attract major pharma alliances, directly impacting the company's licensing pipeline and supporting its broader ambitions in peptide drug discovery, key factors in offsetting the volatility and risks around clinical progress and profitability.

However, despite these clinical and business achievements, questions remain about the impact of persistent operating losses and cash burn on future funding access...

Read the full narrative on PeptiDream (it's free!)

PeptiDream's narrative projects ¥53.3 billion revenue and ¥16.1 billion earnings by 2028. This requires 40.9% yearly revenue growth and a ¥21.1 billion earnings increase from ¥-5.0 billion today.

Uncover how PeptiDream's forecasts yield a ¥3414 fair value, a 107% upside to its current price.

Exploring Other Perspectives

TSE:4587 Earnings & Revenue Growth as at Oct 2025

Simply Wall St Community members provided two fair value estimates for PeptiDream, ranging widely from ¥485 to ¥4,854 per share. With the company still reporting losses, your view on PeptiDream’s prospects may depend on how you weigh upcoming clinical and licensing milestones, explore what other investors are signaling to see where you stand.

Explore 2 other fair value estimates on PeptiDream - why the stock might be worth over 2x more than the current price!

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This article by Simply Wall St is general in nature. We provide commentary based on historical data and analyst forecasts only using an unbiased methodology and our articles are not intended to be financial advice. It does not constitute a recommendation to buy or sell any stock, and does not take account of your objectives, or your financial situation. We aim to bring you long-term focused analysis driven by fundamental data. Note that our analysis may not factor in the latest price-sensitive company announcements or qualitative material. Simply Wall St has no position in any stocks mentioned.

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