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US Investments And New Product Launches Will Shape Future Markets

Published
17 Jul 24
Updated
03 Sep 25
AnalystConsensusTarget's Fair Value
US$102.33
20.8% undervalued intrinsic discount
10 Sep
US$81.02
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1Y
-31.3%
7D
-3.7%

Author's Valuation

US$102.3

20.8% undervalued intrinsic discount

AnalystConsensusTarget Fair Value

Last Update03 Sep 25
Fair value Increased 1.92%

Merck’s analyst price target edged up to $101.75, driven by positive sentiment around the Verona Pharma acquisition’s boost to the respiratory portfolio, ongoing digital and oncology partnerships, and stable vaccine outlook.


Analyst Commentary


  • Bullish analysts point to Merck’s $10B acquisition of Verona Pharma, seeing Verona’s Ohtu as a strategic anchor drug to expand Merck’s respiratory franchise and enhance competitiveness against major therapeutics in the space.
  • Bullish analysts highlight Merck's ongoing oncology partnership with Moderna and the successful launch of enflonsia as supportive of the current outlook for both companies.
  • Analysts note Merck’s commitment to Veeva Vault CRM as indicative of the company’s long-term digital transformation strategy, aligning it with a majority of top pharmaceutical peers.
  • The absence of an FDA panel vote on lowering Gardasil doses is seen as a positive for Merck’s HPV vaccine franchise, maintaining current sales potential amid previously flagged dosing concerns.
  • Increased interest among veterinarians in Merck’s upcoming Atopic Dermatitis JAK inhibitor is seen as a competitive threat to Zoetis, indicating growing strength in Merck’s animal health pipeline.

What's in the News


  • The Trump administration is expected to announce pharmaceutical tariffs and sector-specific import restrictions within weeks, which could impact Merck and other large-cap drugmakers (Reuters, Aug 13, 2025).
  • U.S. officials are negotiating with pharma companies, including Merck, to raise medicine prices abroad through "most favored nation" pricing, aiming to lower domestic drug expenses (Reuters, Aug 8, 2025).
  • The White House is considering imposing a 1%-5% fee on patent holders, which would substantially increase costs for pharma companies that depend on patent protections, such as Merck (WSJ, Jul 28, 2025).
  • Drug tariffs could be imposed as early as August 1, with plans for initially low rates escalating after a year; these tariffs would directly impact Merck and its pharmaceutical peers (Bloomberg, Jul 16, 2025).
  • Direct U.S. support for global HIV programs has been cut, undermining a potential breakthrough year for treatments and affecting companies developing HIV drugs, including Merck (NYT, Jun 25, 2025).

Valuation Changes


Summary of Valuation Changes for Merck

  • The Consensus Analyst Price Target remained effectively unchanged, moving only marginally from $100.41 to $101.75.
  • The Future P/E for Merck remained effectively unchanged, moving only marginally from 12.15x to 12.29x.
  • The Consensus Revenue Growth forecasts for Merck remained effectively unchanged, moving only marginally from 4.3% per annum to 4.2% per annum.

Key Takeaways

  • Merck's strategic investments and acquisitions have tripled its pipeline, aiming to significantly drive earnings growth through blockbuster potential products.
  • Robust R&D and new product launches are expected to maintain leadership in oncology, boosting revenue and enhancing long-term margins.
  • Merck faces challenges with declining GARDASIL sales, potential tariffs, strong competition, KEYTRUDA's exclusivity loss, and pricing pressures in international markets.

Catalysts

About Merck
    Operates as a healthcare company worldwide.
What are the underlying business or industry changes driving this perspective?
  • Merck plans to bring over 20 new growth drivers to market in the coming years, most of which have blockbuster potential, which could significantly boost future revenue.
  • The company is making strategic investments in manufacturing, including $9 billion in U.S. projects through 2028, which may improve net margins by optimizing supply chains and reducing potential tariff impacts.
  • With its acquisition and licensing strategy, Merck has nearly tripled its late-phase pipeline since 2021, which is expected to have a potential commercial opportunity of over $50 billion by the mid-2030s, driving earnings growth.
  • The ongoing strong launches of key new products, such as WINREVAIR and CAPVAXIVE, are positively impacting revenues and are expected to support further growth in the coming years.
  • Merck's proactive steps in business development, combined with robust R&D efforts, are aimed at maintaining and expanding its leadership in oncology and other therapeutic areas, potentially enhancing long-term earnings and net margins.

Merck Earnings and Revenue Growth

Merck Future Earnings and Revenue Growth

Assumptions

How have these above catalysts been quantified?
  • Analysts are assuming Merck's revenue will grow by 4.2% annually over the next 3 years.
  • Analysts assume that profit margins will increase from 25.8% today to 33.7% in 3 years time.
  • Analysts expect earnings to reach $24.3 billion (and earnings per share of $9.89) by about September 2028, up from $16.4 billion today. However, there is some disagreement amongst the analysts with the more bearish ones expecting earnings as low as $20.2 billion.
  • In order for the above numbers to justify the analysts price target, the company would need to trade at a PE ratio of 12.3x on those 2028 earnings, down from 12.9x today. This future PE is lower than the current PE for the GB Pharmaceuticals industry at 19.0x.
  • Analysts expect the number of shares outstanding to decline by 1.26% per year for the next 3 years.
  • To value all of this in today's terms, we will use a discount rate of 6.78%, as per the Simply Wall St company report.

Merck Future Earnings Per Share Growth

Merck Future Earnings Per Share Growth

Risks

What could happen that would invalidate this narrative?
  • Merck faces a decline in GARDASIL sales in China, driven by higher channel inventories and soft demand, affecting global revenue growth.
  • The potential impact of additional tariffs, especially if they target pharmaceuticals, could introduce costs and affect net margins and earnings in the short to medium term.
  • Strong global competition poses a risk to Merck’s pipeline and revenue streams, particularly if new entrants capture market share before Merck's similar offerings are approved.
  • The eventual loss of exclusivity (LOE) for KEYTRUDA could lead to significant revenue decline if the pipeline doesn't compensate for this gap.
  • The disparity between U.S. and global drug prices, coupled with potential changes in international pricing regulations, could pressure Merck’s pricing strategies and revenues in key markets.

Valuation

How have all the factors above been brought together to estimate a fair value?
  • The analysts have a consensus price target of $102.333 for Merck based on their expectations of its future earnings growth, profit margins and other risk factors. However, there is a degree of disagreement amongst analysts, with the most bullish reporting a price target of $141.0, and the most bearish reporting a price target of just $82.0.
  • In order for you to agree with the analyst's consensus, you'd need to believe that by 2028, revenues will be $72.0 billion, earnings will come to $24.3 billion, and it would be trading on a PE ratio of 12.3x, assuming you use a discount rate of 6.8%.
  • Given the current share price of $84.61, the analyst price target of $102.33 is 17.3% higher.
  • We always encourage you to reach your own conclusions though. So sense check these analyst numbers against your own assumptions and expectations based on your understanding of the business and what you believe is probable.

How well do narratives help inform your perspective?

Disclaimer

AnalystConsensusTarget is a tool utilizing a Large Language Model (LLM) that ingests data on consensus price targets, forecasted revenue and earnings figures, as well as the transcripts of earnings calls to produce qualitative analysis. The narratives produced by AnalystConsensusTarget are general in nature and are based solely on analyst data and publicly-available material published by the respective companies. These scenarios are not indicative of the company's future performance and are exploratory in nature. Simply Wall St has no position in the company(s) mentioned. Simply Wall St may provide the securities issuer or related entities with website advertising services for a fee, on an arm's length basis. These relationships have no impact on the way we conduct our business, the content we host, or how our content is served to users. The price targets and estimates used are consensus data, and do not constitute a recommendation to buy or sell any stock, and they do not take account of your objectives, or your financial situation. Note that AnalystConsensusTarget's analysis may not factor in the latest price-sensitive company announcements or qualitative material.

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